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Purified anti-HIV gp120 Antibody (Previously Covance catalog# MMS-193P)

Pricing & Availability
Clone
ED8.D4 (See other available formats)
Regulatory Status
RUO
Other Names
HTLV-III gp120, Envelope Glycoprotein gp120, HIV, gp120(HIV), HIV Envelope Glycoprotein gp120, HTLV III gp120, env Protein gp120, HIV, gp120 Envelope Glycoprotein, HIV, gp120, HTLV-III
Previously
Covance Catalog# MMS-193P
Isotype
Mouse IgG1
Ave. Rating
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Product Citations
publications
Cat # Size Price Save
906801 250 µL ¥77,440
Description

Glycoprotein 120, or gp120, is a human immunodeficiency virus (HIV) envelope protein derived from the proteolytic cleavage of gp160. It attaches HIV to host lymphoid cells by binding to the primary receptor CD4. This binding interaction induces a structural rearrangement creating another high affinity binding site for a chemokine co-receptor like CXCR4 and/or CCR5. The protein also serves as a ligand for CD209/DC-SIGN and CLEC4M/DC-SIGNR. CD209 in particular is an important interaction as dendritic cells loaded with viral particles can migrate to lymph nodes to provide access to T cells for infection.

Product Details
Technical data sheet

Product Details

Verified Reactivity
HIV
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
This antibody was raised against a peptide corresponding to the amino acid sequence 427-448 of the gp120 protein.
Formulation
Phosphate-buffered solution + 0.03% Thimerosal.
Preparation
The antibody was purified by affinity chromatography.
Concentration
1 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C. Please note the storage condition for this antibody has been changed from -20°C to between 2°C and 8°C. You can also check your vial or your CoA to find the most accurate storage condition for this antibody.
Application

WB, ELISA
Recommended Usage

Each lot of this antibody is quality control tested by Western blotting.

The optimal working dilution should be determined for each specific assay condition.
• WB: 1:500*
• ELISA: 1:500
 

Application Notes

This antibody is effective in immunoblotting and ELISA.

*Predicted MW = 120 kD

Application References

(PubMed link indicates BioLegend citation)
  1. Not Published
RRID
AB_2565069 (BioLegend Cat. No. 906801)

Antigen Details

Biology Area
Bacterial proteins and Toxins, Cell Biology, Signal Transduction
Gene ID
155971 View all products for this Gene ID
UniProt
View information about HIV gp120 on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 3    Revision Date: 09/21/2023

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

8999 BioLegend Way, San Diego, CA 92121 www.biolegend.com
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

  • Purified anti-HIV gp120

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