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FITC anti-human CD26 Antibody

Pricing & Availability
Clone
BA5b (See other available formats)
Regulatory Status
RUO
Workshop
VI N-L078
Other Names
ADA-binding protein, DPP IV ectoenzyme, EC 3.4.14.5
Isotype
Mouse IgG2a, κ
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Product Citations
publications
BA5b_FITC_071805
Human peripheral blood lymphocytes stained with BA5b FITC
  • BA5b_FITC_071805
    Human peripheral blood lymphocytes stained with BA5b FITC
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302704 100 tests 169€
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Description

CD26 is a 110 kD type II membrane protein also known as ADA-binding protein and dipeptidyl peptidase IV (DPPIV). It is a member of the peptidase and ectoenzyme family. CD26 is expressed on the membrane of mature thymocytes, T lymphocytes (upregulated upon activation), B cells, NK cells, and macrophages. CD26 cleaves off N-terminal X-Pro and X-Ala dipeptides from polypeptides. It plays an integral role as a costimulatory molecule in T cell activation. CD26 may interact with extracellular matrix proteins such as fibronectin or collagen, CD45 and ADA.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Blue Laser (488 nm)
Application References

(PubMed link indicates BioLegend citation)
  1. Kishimoto T, et al. Eds. 1997. Leucocyte Typing VI. Garland Press. London.
  2. Schlossman S, et al. Eds. 1995. Leucocyte Typing V. Oxford University Press. New York.
Product Citations
  1. Fu H, et al. 2023. Regen Ther. 22:7. PubMed
  2. Musvosvi M, et al. 2023. Nat Med. 29:258. PubMed
  3. Gur C, et al. 2022. Cell. 185:1373. PubMed
  4. Wragg KM, et al. 2020. Cell Reports. 31(11):107773. PubMed
  5. Xin Y, et al. 2017. Exp Cell Res. 10.1016/j.yexcr.2017.04.021. PubMed
  6. Tardif V, et al. 2019. Nat Commun. 10:823. PubMed
  7. Park J, et al. 2016. Proc Natl Acad Sci U S A. 113: 4482-4487. PubMed
  8. Lo ST, et al. 2021. Mol Imaging Biol. 23:230. PubMed
  9. Borrelli MR, et al. 2020. Aesthet Surg J. 369:40. PubMed
  10. Pfaender S, et al. 2020. Nat Microbiol. 1.131944444. PubMed
  11. Stoyanova T, et al. 2013. Proc Natl Acad Sci U S A. 110:20111. PubMed
  12. Khuzwayo S, et al. 2021. Front Immunol. 12:631410. PubMed
  13. Henry G, et al. 2017. Prostate. 77:1344. PubMed
  14. Angueira AR, et al. 2021. Nat Metab. 3:469. PubMed
  15. Jiang J, et al. 2016. Sci Rep. 6: 32320. PubMed
RRID
AB_314288 (BioLegend Cat. No. 302704)

Antigen Details

Structure
Peptidases and ectoenzyme families, type II glycoprotein, 110 kD
Distribution

Thymocyte subset, memory T cells, B cells, NK cells, epithelial cells, macrophages

Function
Dipeptidyl peptidase, T cell costimulation, HIV entry
Ligand/Receptor
Adenosine-deaminase, collagen
Cell Type
B cells, Epithelial cells, Macrophages, NK cells, T cells, Thymocytes
Biology Area
Costimulatory Molecules, Immunology
Molecular Family
CD Molecules
Antigen References

1. Kameoka J, et al. 1993. Science 261:466.
2. Dang N, et al. 1990. J. Exp. Med. 172:649.

Gene ID
1803 View all products for this Gene ID
UniProt
View information about CD26 on UniProt.org
Go To Top Version: 1    Revision Date: 11.30.2012

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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