- Clone
- SP8 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Syntaxin-1A, neuron-specific antigen HPC-1
- Isotype
- Mouse IgG1
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
827003 | 25 µg | 118€ | ||||
827004 | 100 µg | 249€ |
Syntaxin, also known as syntaxin-1A and neuron-specific antigen HPC-1, is part of the Q-SNARE protein family that participates in exocytosis. Syntaxins have a SNARE domain, an N-terminal regulatory domain, and a single C-terminal transmembrane domain. Syntaxin drives the spontaneous calcium-independent fusion of synaptic vesicles that contain v-SNARE proteins, and may form part of the fusion pore of exocytosis.
Product DetailsProduct Details
- Verified Reactivity
- Human, Mouse, Rat
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- This monoclonal antibody was raised against a crude synaptic preparation from a post-mortem human brain.
- Formulation
- This antibody is provided in 50% glycerol in aqueous buffered solutions with preservatives.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with HRP under optimal conditions.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- Upon receipt, the antibody solution should be stored undiluted at -20°C, and protected from prolonged exposure to light.
- Application
-
WB - Quality tested
IHC-P - Verified - Recommended Usage
-
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.02 - 0.1 µg per ml. For immunohistochemistry on formalin-fixed paraffin-embedded tissue, a concentration range of 5.0 - 10 µg/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
-
This antibody is effective in immunohistochemistry (IHC-P) and western blotting (WB).
-
Application References
(PubMed link indicates BioLegend citation) -
- Honer WG, et al. 1997. Neuroscience 78(1):99-110.
- Honer WG, et al. 1993. Brain Res. 609(1-2):9-20.
- RRID
-
AB_2783400 (BioLegend Cat. No. 827003)
AB_2783400 (BioLegend Cat. No. 827004)
Antigen Details
- Biology Area
- Cell Biology, Neuroscience, Synaptic Biology
- Molecular Family
- Presynaptic proteins
- Gene ID
- 6804 View all products for this Gene ID
- UniProt
- View information about Syntaxin on UniProt.org
Related Pages & Pathways
Pages
Other Formats
View All Syntaxin Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-Syntaxin | SP8 | IHC-P,WB |
HRP anti-Syntaxin | SP8 | WB,IHC-P |
Biotin anti-Syntaxin | SP8 | WB,IHC-P |
Alexa Fluor® 647 anti-Syntaxin | SP8 | IHC-P |
Alexa Fluor® 488 anti-Syntaxin | SP8 | IHC-P |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-Syntaxin
Western blot of purified anti-Syntaxin antibody (clone SP8).... IHC staining of purified anti-Syntaxin antibody (clone SP8) ... IHC staining of purified anti-Syntaxin Antibody (clone SP8) ... IHC staining of purified anti-Syntaxin antibody (clone SP8) ... -
HRP anti-Syntaxin
Western blot of HRP anti-Syntaxin antibody (clone SP8). Lane... IHC staining of HRP anti-Syntaxin antibody (clone SP8) on fo... IHC staining of HRP anti-Syntaxin antibody (clone SP8) on fo... IHC staining of HRP anti-Syntaxin antibody (clone SP8) on fo... -
Biotin anti-Syntaxin
Western blot of Biotin anti-Syntaxin antibody (clone SP8). L... Immunofluorescence staining of Biotin anti-Syntaxin antibody... Immunofluorescence staining of Biotin anti-Syntaxin antibody... Immunofluorescence staining of Biotin anti-Syntaxin antibody... Immunofluorescence staining of Biotin anti-Syntaxin antibody... Immunofluorescence staining of Biotin anti-Syntaxin antibody... -
Alexa Fluor® 647 anti-Syntaxin
IHC staining of Alexa Fluor® 647 anti-Syntaxin antibody (clo... IHC staining of Alexa Fluor® 647 anti-Syntaxin antibody (clo... IHC staining of Alexa Fluor® 647 anti-Syntaxin antibody (clo... -
Alexa Fluor® 488 anti-Syntaxin
IHC staining of Alexa Fluor® 488 anti-Syntaxin antibody (clo... IHC staining of Alexa Fluor® 488 anti-Syntaxin antibody (clo...
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