PE anti-human CD7 Antibody, CD7, 4H9/CD7

Pricing & Availability

Clone: 4H9/CD7 (See other available formats)
Regulatory Status: RUO
Other Names: gp40
Isotype: Mouse IgG2a, κ
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Product Citations: publications

Human peripheral blood lymphocytes stained with CD4 APC and CD7 (clone 4H9/CD7) PE (left), or Mouse IgG2a, κ PE isotype control (right).

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395603

25 tests

74€

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395604

100 tests

196€

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Description

CD7 is a 40 kD type I transmembrane glycoprotein also known as gp40. It is a member of the immunoglobulin superfamily found on T cells, NK cells, thymocytes, hematopoietic progenitors, and monocytes (weakly). CD7 is also expressed on acute lymphocytic leukemia (ALL) and some acute myeloid leukemia (AML) cells. CD7 crosslinking induces a calcium flux in T lymphocytes, presumably as a result of cytoplasmic domain association with PI3-kinase. CD7 costimulation can induce cytokine secretion and modulate cellular adhesion.

Product Details

Technical Data Sheet (pdf)

Product Details

Verified Reactivity: Human
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: T-ALL blast cells
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation: The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
Concentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application: FC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood.
Excitation Laser: Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
RRID: AB_2820048 (BioLegend Cat. No. 395603)
AB_2820048 (BioLegend Cat. No. 395604)

Antigen Details

Structure: Ig superfamily, type I transmembrane glycoprotein, 40 kD
Distribution: T cells, NK cells, thymocytes, hematopoietic progenitors, myeloid leukemic cell subsets
Function: T cell activation
Ligand/Receptor: Cytoplasmic domain associates with P13-kinase
Cell Type: Hematopoietic stem and progenitors, Leukemia, NK cells, T cells, Thymocytes
Biology Area: Costimulatory Molecules, Immunology
Molecular Family: CD Molecules
Antigen References: Barclay N, et al. 1993. The Leucocyte Antigen FactsBook. Academic Press Inc. San Diego.

Stillwell R and Bierer BE. 2001. Immunol Res. 24:31-52.

Rabinowich H, et al. 1994. J Immunol. 152:517-26.
Gene ID: 924 View all products for this Gene ID
UniProt: View information about CD7 on UniProt.org

Documentation

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Related Protocols

Cell Surface Flow Cytometry Staining Protocol

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Description	Clone	Applications

Related Pages & Pathways

Pathways

Related FAQs

What type of PE do you use in your conjugates?: We use R-PE in our conjugates.

Other Formats

View All CD7 Reagents Request Custom Conjugation

Description	Clone	Applications
Purified anti-human CD7	4H9/CD7	FC
PE anti-human CD7	4H9/CD7	FC
APC anti-human CD7 Antibody	4H9/CD7	FC
PerCP/Cyanine5.5 anti-human CD7 Antibody	4H9/CD7	FC
PE/Cyanine7 anti-human CD7	4H9/CD7	FC
FITC anti-human CD7	4H9/CD7	FC

Certificate of Analysis

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Go To Top Version: 1 Revision Date: 10.23.2019

For Research Use Only. Not for diagnostic or therapeutic use.

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