- Clone
- DL-101 (See other available formats)
- Regulatory Status
- RUO
- Workshop
- V B045
- Other Names
- Syndecan-1, B-B4
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
352317 | 25 tests | 147€ | ||||
352318 | 100 tests | 344€ |
CD138, a member of the syndecan protein family, is a type I integral membrane heparin sulfate proteoglycan also known as Syndecan-1. Syndecan-1 participates in cell proliferation, cell migration, and cell-matrix adhesion via interaction with collagen, fibronectin, and other soluble molecules (such as FGF-basic). It is expressed on normal and malignant human plasma cells, pre-B cells, epithelial cells, and endothelial cells.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Reported Reactivity
- African Green, Baboon, Cynomolgus
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Human SDC1
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
- Excitation Laser
-
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
-
The epitope recognized by MI15 is found within the ectodomain of the CD138 core protein. It has been reported that MI15 blocks the binding of clone B-B4 but not clone DL-101 by flow cytometric analysis. Clones DL-101 and MI15 exhibit differential staining patterns on in vitro generated plasma cells and some CD138+ cell lines.2
Additional reported applications (for the relevant formats of this clone) include: immunohistochemical staining in paraffin blocks of tissue sections1. -
Application References
(PubMed link indicates BioLegend citation) -
- Osama MA. 2010. Int. J. Clin. Exp. Pathol. 3:280. (IHC)
- Itoua MR, et al. 2014. Biomed. Res. Int. 2014:536482. PubMed
- Product Citations
-
- RRID
-
AB_2687339 (BioLegend Cat. No. 352317)
AB_2687339 (BioLegend Cat. No. 352318)
Antigen Details
- Structure
- 100-200 kD type I integral transmembrane glycoprotein
- Distribution
-
Plasma cells, pre-B cells, epithelial cells, endothelial cells
- Function
- Adhesion, control cell morphology, regulate cell growth
- Ligand/Receptor
- FGFb, collagen, fibronectin
- Cell Type
- B cells, Endothelial cells, Epithelial cells, Plasma cells
- Biology Area
- Cell Adhesion, Cell Biology, Immunology
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. Sanderson RD, et al. 1992. Cell. Regul. 1:27.
2. Zola H, et al. 2007. Leukocyte and Stromal Cell Molecules: The CD Markers Wiley-Liss A John Wiley & Sons Inc, Publication. - Gene ID
- 6382 View all products for this Gene ID
- UniProt
- View information about CD138 on UniProt.org
Related FAQs
Other Formats
View All CD138 Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-human CD138 (Syndecan-1) | DL-101 | FC,IHC-P |
FITC anti-human CD138 (Syndecan-1) | DL-101 | FC |
PE anti-human CD138 (Syndecan-1) | DL-101 | FC |
APC anti-human CD138 (Syndecan-1) | DL-101 | FC |
PerCP/Cyanine5.5 anti-human CD138 (Syndecan-1) | DL-101 | FC |
Purified anti-human CD138 (Syndecan-1) (Maxpar® Ready) | DL-101 | FC,CyTOF® |
PE/Cyanine7 anti-human CD138 (Syndecan-1) | DL-101 | FC |
PE/Dazzle™ 594 anti-human CD138 (Syndecan-1) | DL-101 | FC |
Alexa Fluor® 647 anti-human CD138 (Syndecan-1) | DL-101 | FC |
APC/Fire™ 750 anti-human CD138 (Syndecan-1) | DL-101 | FC |
Biotin anti-human CD138 (Syndecan-1) | DL-101 | FC |
Alexa Fluor® 594 anti-human CD138 (Syndecan-1) | DL-101 | IHC-P |
TotalSeq™-A0831 anti-human CD138 (Syndecan-1) | DL-101 | PG |
TotalSeq™-C0831 anti-human CD138 (Syndecan-1) | DL-101 | PG |
TotalSeq™-B0831 anti-human CD138 (Syndecan-1) Antibody | DL-101 | PG |
TotalSeq™-Bn0831 anti-human CD138 (Syndecan-1) | DL-101 | SB |
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Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
-
Purified anti-human CD138 (Syndecan-1)
Human myeloma cell line U266 was stained with purified CD138... Human paraffin-embedded colon tissue slices were prepared wi... -
FITC anti-human CD138 (Syndecan-1)
Human myeloma cell line U266 was stained with CD138 (clone D... -
PE anti-human CD138 (Syndecan-1)
Human myeloma cell line U266 was stained with CD138 (clone D... -
APC anti-human CD138 (Syndecan-1)
Human myeloma cell line U266 was stained with CD138 (clone D... -
PerCP/Cyanine5.5 anti-human CD138 (Syndecan-1)
Human myeloma cell line U266 was stained with CD138 (Syndeca... -
Purified anti-human CD138 (Syndecan-1) (Maxpar® Ready)
U266 (blue) and Jurkat (red) cells stained with 145Nd-anti-C... -
PE/Cyanine7 anti-human CD138 (Syndecan-1)
Human myeloma cell line U266 was stained with CD138 (clone D... -
PE/Dazzle™ 594 anti-human CD138 (Syndecan-1)
Human myeloma cell line U266 was stained with CD138 (clone D... -
Alexa Fluor® 647 anti-human CD138 (Syndecan-1)
Human myeloma cell line U266 was stained with CD138 (clone D... -
APC/Fire™ 750 anti-human CD138 (Syndecan-1)
Human myeloma cell line U266 was stained with CD138 (clone D... -
Biotin anti-human CD138 (Syndecan-1)
Human myeloma cell line U266 was stained with CD138 (clone D... -
Alexa Fluor® 594 anti-human CD138 (Syndecan-1)
Human paraffin-embedded colon tissue slices were prepared wi... -
TotalSeq™-A0831 anti-human CD138 (Syndecan-1)
-
TotalSeq™-C0831 anti-human CD138 (Syndecan-1)
-
TotalSeq™-B0831 anti-human CD138 (Syndecan-1) Antibody
-
TotalSeq™-Bn0831 anti-human CD138 (Syndecan-1)
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