- Clone
- 19F2 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- BCM, TNFRSF17
- Isotype
- Mouse IgG2a, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
357511 | 25 tests | 141€ | ||||
357512 | 100 tests | 329€ |
CD269, also known as B cell maturation antigen (BCMA), is a 27 kD, single pass transmembrane protein with one TNFR-Cys repeat on its extracellular domain. CD269 is a B cell maturation factor, essential for the long-term survival of plasma cells. It is expressed by plasmablasts, plasma cells, and germinal center B cells. The ligands of CD269 are BAFF and APRIL, and its cytoplasmic domain binds several of the TRAF family members.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- BCMA-mouse IgG Fc fusion protein
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE/Dazzle™ 594 under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
* PE/Dazzle™ 594 has a maximum excitation of 566 nm and a maximum emission of 610 nm. - Excitation Laser
-
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Product Citations
-
- RRID
-
AB_2566531 (BioLegend Cat. No. 357511)
AB_2566531 (BioLegend Cat. No. 357512)
Antigen Details
- Structure
- Single pass transmembrane protein, member of the TNFR superfamily, 1 TNFR-Cys domain, 27 kD
- Distribution
-
Plasmablasts, plasma cells, germinal center B cells
- Function
- B cell maturation factor, essential for survival of plasma cells
- Interaction
- Associates with several TRAF family members
- Ligand/Receptor
- BAFF, APRIL
- Cell Type
- B cells, Plasma cells
- Biology Area
- Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
1. Coquery CM and Erickson LD. 2012. Crit. Rev. Immunol. 32:287.
2. Notas G, et al. 2012. J. Immunol. 189:4748.
3. Rickert RC, et al. 2011. Immunol. Rev. 244:115.
4. Mesin L, et al. 2011. J. Immunol. 187:2867. - Gene ID
- 608 View all products for this Gene ID
- UniProt
- View information about CD269 on UniProt.org
Related FAQs
Other Formats
View All CD269 Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-human CD269 (BCMA) | 19F2 | FC |
PE anti-human CD269 (BCMA) | 19F2 | FC |
APC anti-human CD269 (BCMA) | 19F2 | FC |
PE/Cyanine7 anti-human CD269 (BCMA) | 19F2 | FC |
PerCP/Cyanine5.5 anti-human CD269 (BCMA) | 19F2 | FC |
PE/Dazzle™ 594 anti-human CD269 (BCMA) | 19F2 | FC |
Biotin anti-human CD269 (BCMA) | 19F2 | FC |
APC/Fire™ 750 anti-human CD269 (BCMA) | 19F2 | FC |
Alexa Fluor® 647 anti-human CD269 (BCMA) | 19F2 | FC |
Brilliant Violet 421™ anti-human CD269 (BCMA) | 19F2 | FC |
TotalSeq™-A0056 anti-human CD269 (BCMA) | 19F2 | PG |
TotalSeq™-C0056 anti-human CD269 (BCMA) | 19F2 | PG |
TotalSeq™-B0056 anti-human CD269 (BCMA) | 19F2 | PG |
KIRAVIA Blue 520™ anti-human CD269 (BCMA) Antibody | 19F2 | FC |
PE/Cyanine5 anti-human CD269 (BCMA) | 19F2 | FC |
PE/Fire™ 810 anti-human CD269 (BCMA) | 19F2 | FC |
Brilliant Violet 650™ anti-human CD269 (BCMA) | 19F2 | FC |
Brilliant Violet 785™ anti-human CD269 (BCMA) | 19F2 | FC |
Brilliant Violet 605™ anti-human CD269 (BCMA) | 19F2 | FC |
TotalSeq™-D0056 anti-human CD269 (BCMA) | 19F2 | PG |
Customers Also Purchased
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
-
Purified anti-human CD269 (BCMA)
Human myeloma cell line U266 was stained with purified CD269... -
PE anti-human CD269 (BCMA)
Human myeloma cell line U266 was stained with CD269 (clone 1... -
APC anti-human CD269 (BCMA)
Human myeloma cell line U266 was stained with CD269 (clone 1... -
PE/Cyanine7 anti-human CD269 (BCMA)
Human myeloma cell line U266 was stained with CD269 (clone 1... -
PerCP/Cyanine5.5 anti-human CD269 (BCMA)
Human myeloma cell line U266 was stained with CD269 (BCMA, c... -
PE/Dazzle™ 594 anti-human CD269 (BCMA)
Human myeloma cell line U266 was stained with CD269 (clone 1... -
Biotin anti-human CD269 (BCMA)
Human myeloma cell line U266 was stained with biotinylated C... -
APC/Fire™ 750 anti-human CD269 (BCMA)
Human myeloma cell line U266 was stained with CD269 (clone 1... -
Alexa Fluor® 647 anti-human CD269 (BCMA)
Human myeloma cell line, U266, was stained with CD269 (Clone... -
Brilliant Violet 421™ anti-human CD269 (BCMA)
Human myeloma cell line, U266, was stained with CD269 (clone... -
TotalSeq™-A0056 anti-human CD269 (BCMA)
-
TotalSeq™-C0056 anti-human CD269 (BCMA)
-
TotalSeq™-B0056 anti-human CD269 (BCMA)
-
KIRAVIA Blue 520™ anti-human CD269 (BCMA) Antibody
Human myeloma cell line U266 was stained with anti-human CD2... -
PE/Cyanine5 anti-human CD269 (BCMA)
Human myeloma cell line, U266, was stained with anti-human C... -
PE/Fire™ 810 anti-human CD269 (BCMA)
Human myeloma cell line, U266, was stained with anti-human C... -
Brilliant Violet 650™ anti-human CD269 (BCMA)
U266 cells (a myeloma cell line) were stained with anti-huma... -
Brilliant Violet 785™ anti-human CD269 (BCMA)
U266 cells (a myeloma cell line) were stained with anti-huma... -
Brilliant Violet 605™ anti-human CD269 (BCMA)
U266 cells (a myeloma cell line) were stained with anti-huma... -
TotalSeq™-D0056 anti-human CD269 (BCMA)
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