- Clone
- 14H4-1-2 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- MDL1, MDL-1, CLECSFS
- Isotype
- Mouse IgG2b, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
371707 | 25 tests | 165€ | ||||
371708 | 100 tests | 344€ |
CLEC5A/MDL1 is a 40 kD transmembrane glycoprotein belonging to the C-type lectin superfamily; alternative splice variants have been described but their full-length sequence has not been determined. CLEC5A mediates inflammatory responses during autoimmune arthritis and upon binding to Dengue and Japanese encephalitis viruses. It also positively regulates osteoclastogenesis.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Partial recombinant protein (28 — 188 a.a.) expressed in 293E cells.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE/Dazzle™ 594 under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
* PE/Dazzle™ 594 has a maximum excitation of 566 nm and a maximum emission of 610 nm. - Excitation Laser
-
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- RRID
-
AB_2922587 (BioLegend Cat. No. 371707)
AB_2922587 (BioLegend Cat. No. 371708)
Antigen Details
- Structure
- Approximately 21 kD C-type lectin domain-containing glyocoprotein.
- Distribution
-
Expressed on immature myeloid cells, monocytes, macrophages, dendritic cells, neutrophils, NK cells, and osteocytes.
- Function
- Cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response.
- Interaction
- DAP12, TYROBP
- Ligand/Receptor
- Dengue Virus Envelope Proteins
- Cell Type
- Dendritic cells, Macrophages, Monocytes, Neutrophils, NK cells
- Biology Area
- Cell Adhesion, Cell Biology, Immunology
- Antigen References
-
1. Chen DY, et al. 2014. PLoS One e86105.
2. Wu MF, et al. 2013. Blood 121:95.
3. Yang YL, et al. 2012. J. Biomed. Biotechnol. 2012:398628.
4. Watson AA, et al. 2011. J. Biol. Chem. 286(27):24208. - Gene ID
- 23601 View all products for this Gene ID
- UniProt
- View information about CLEC5A on UniProt.org
Related FAQs
Other Formats
View All CLEC5A Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-human CLEC5A | 14H4-1-2 | FC |
TotalSeq™-C1177 anti-human CLEC5A Antibody | 14H4-1-2 | PG |
PE anti-human CLEC5A | 14H4-1-2 | FC |
PE/Dazzle™ 594 anti-human CLEC5A | 14H4-1-2 | FC |
APC anti-human CLEC5A | 14H4-1-2 | FC |
PE/Cyanine7 anti-human CLEC5A | 14H4-1-2 | FC |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
-
Purified anti-human CLEC5A
Human peripheral blood monocytes were stained with purified ... -
TotalSeq™-C1177 anti-human CLEC5A Antibody
-
PE anti-human CLEC5A
Human peripheral blood monocytes were stained with anti-huma... -
PE/Dazzle™ 594 anti-human CLEC5A
Human peripheral blood monocytes were stained with anti-huma... -
APC anti-human CLEC5A
Human peripheral blood monocytes were stained with anti-huma... -
PE/Cyanine7 anti-human CLEC5A
Human peripheral blood monocytes were stained with anti-huma...
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