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Purified anti-mouse CD3ε Antibody

Pricing & Availability
Clone
145-2C11 (See other available formats)
Regulatory Status
RUO
Other Names
CD3ε, T3, CD3
Isotype
Armenian Hamster IgG
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Product Citations
publications
145-2C11_Pure_021606
C57BL/6 mouse splenocytes were stained with purified CD3e (clone 145-2C11) (filled histogram) or Armenian hamster IgG isotype control (open histogram), followed by anti-Armenian hamster IgG FITC.
  • 145-2C11_Pure_021606
    C57BL/6 mouse splenocytes were stained with purified CD3e (clone 145-2C11) (filled histogram) or Armenian hamster IgG isotype control (open histogram), followed by anti-Armenian hamster IgG FITC.
  • 145-2C11_PURE_CD3e_Antibody_IHC-F_033017
    C57BL/6 mouse frozen spleen section was fixed with 4% paraformaldehyde (PFA) for ten minutes at room temperature and blocked with 5% FBS for 30 minutes at room temperature. Then the section was stained with 10 µg/mL of purified anti-mouse CD3ε (clone 145-2C11) and 10 µg/mL of Alexa Fluor® 488 anti-mouse/human CD45R/B220 (clone RA3-6B2) (green) overnight at 4°C, followed by 2.5 µg/mL of Alexa Fluor® 594 Goat anti-hamster (Armenian) IgG (clone Poly4055) (red) for two hours at room temperature. The image was captured by 10X objective.
  • 145-2C11_PURE_CD3e_Antibody_IHC-F_2_102518
    Fresh, frozen mouse spleen was stained with purified CD3ε clone 145-2C11 conjugated and detected with a Cy3 CODEX™ oligonucleotide duplex (red). Samples were counterstained with B220 A647 (green). Data generated at Akoya Biosciences, Inc. using the CODEX™ technology.
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100301 50 µg 20€
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100302 500 µg 58€
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Description

CD3ε is a 20 kD transmembrane protein, also known as CD3 or T3. It is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3ε forms a TCR complex by associating with the CD3δ, γ and ζ chains, as well as the TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Armenian Hamster
Immunogen
H-2Kb-specific mouse cytotoxic T lymphocyte clone BM10-37
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The CD3ε antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
IHC-F - Verified
IP, Activ, Block, WB, ICC - Reported in the literature, not verified in house
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per million cells in 100 µl volume. For immunohistochemical staining on frozen tissue sections, the suggested use of this reagent is 5.0 - 10 µg per ml. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Clone 145-2C11 is useful for in vitro blocking of target-specific CTL-mediated cell lysis1, as well as T cell activation assays, inducing proliferation and cytokine production1,2,7,12,16. It also induces apoptosis in immature thymocytes32,  and in vivo T cell depletion8-10. Additional reported applications (for relevant formats of this clone) include: immunoprecipitation1, immunohistochemical staining14,15 of acetone-fixed frozen sections and zinc-fixed paraffin-embedded sections, Western blotting4, complement-mediated cytotoxicity6, in vitro and in vivo stimulation of T cells1,2,7,12,16, immunofluorescent staining5, and in vivo T cell depletion8-10. The 145-2C11 antibody has been reported to block the binding of 17A2 antibody to CD3 epsilon-specific T cells11. Clone 145-2C11 is not recommended for formalin-fixed paraffin embedded sections. The LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 100314). For in vivo studies or highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 100340) with a lower endotoxin limit than standard LEAF™ purified antibodies (Endotoxin <0.01 EU/µg).

Application References

(PubMed link indicates BioLegend citation)
  1. Leo O, et al. 1987. P. Natl. Acad. Sci. USA 84:1374. (IP, Activ, Block)
  2. Kruisbeek AM, et al. 1991. In Current Protocols in Immunology. 3.12.1. (Activ)
  3. Duke RC, et al. 1995. Current Protocols in Immunology. 3.17.1.
  4. Salvadori S, et al. 1994. J. Immunol. 153:5176. (WB)
  5. Payer E, et al. 1991. J. Immunol. 146:2536. (IF)
  6. Jacobs H, et al. 1994. Eur. J. Immunol. 24:934. (CMCD)
  7. Vossen ACTM, et al. 1995. Eur. J. Immunol. 25:1492. (Activ)
  8. Henrickson M, et al. 1995. Transplantation 60:828. (Deplete)
  9. Kinnaert P, et al. 1996. Transpl. Int. 9:386. (Deplete)
  10. Han WR, et al. 1999. Transpl. Immunol. 7:207. (Deplete)
  11. Miescher GC, et al. 1989. Immunol. Lett. 23:113. (Block)
  12. Terrazas LI, et al. 2005. Intl. J. Parasitology. 35:1349. (Activ)
  13. Ko SY, et al. 2005. J. Immunol. 175:3309.
  14. Podd BS, et al. 2006. J. Immunol. 176:6532. (IHC-F)
  15. Tilley SL, et al. 2007. J. Immunol. 178:3208. (IHC-F)
  16. Wang W, et al. 2007. J. Immunol. 178:4885. (Activ)
  17. Xiao S, et al. 2007. J. Exp. Med. 204:1691.
  18. Chappaz S, et al. 2007. Blood doi:10.1182/blood-2007-02-074245. (FC) PubMed.
  19. Curtsinger JM, et al.2005. J. Immunol. 175:4392. PubMed
  20. Guo Y, et al. 2008. Blood 112:480. PubMed
  21. Kenna TJ, et al. 2008. Blood 111:2091.
  22. Perchonock CE, et al. 2007. J. Immunol. 179:1768. PubMed
  23. Perchonock GE, et al. 2006. Mol. Cell. Biol. 26:6005. PubMed
  24. Kanaya T, et al. 2008. Am. J. Physiol. Gastrointest. Liver Physiol. 295:G273. PubMed
  25. de Koning BA, et al. 2006. Int. Immunol. 18:941. PubMed
  26. Schulteis RD, et al. 2008. Blood 295:G273. PubMed
  27. Qi Q, et al. 2009. Blood 114:564. PubMed
  28. Helmersson S, et al. 2013. Am J Pathol. 9440:123. Pubmed
  29. Wu S, et al. 2014. Clin Vaccine Immunol. 21:156. PubMed
  30. Yan J, et al. 2014. Vaccine. 32:2833. PubMed
  31. Guiterrez DA, et al. 2014. Diaebetes. 63:3827. PubMed
  32. Shi YF, et al. 1991. J Immunol. 146:3340. (Apop)
Product Citations
  1. Akiyama C, et al. 2019. J Immunol. 203:835. PubMed
  2. Bergfeld A, et al. 2017. Front Microbiol. 0.919444444. PubMed
  3. Chemnitz J, et al. 2019. Sci Rep. 3.745138889. PubMed
  4. Arnold IC, et al. 2019. PLoS Pathog. 15:e1007866. PubMed
  5. Wolf Y, et al. 2017. J Exp Med. 214:905. PubMed
  6. Kim K, et al. 2016. PLoS One. 11: 0148576. PubMed
  7. Sandu I, et al. 2020. Nat Commun. 11:4454. PubMed
  8. Kobayashi A, et al. 2021. Front Immunol. 12:650856. PubMed
  9. Paterson MJ, et al. 2020. PLoS Pathog. 16:e1008733. PubMed
  10. Tian J, et al. 2021. Autophagy. 17:2586. PubMed
  11. Tersteegen A, et al. 2021. Infect Immun. 89:. PubMed
  12. Liu CJ, et al. 2020. Neuro Oncol. 22:1276. PubMed
  13. Collin R, et al. 2020. J Immunol. 205:133. PubMed
  14. Malinczak CA, et al. 2021. J Immunol. 206:1315. PubMed
  15. Li H, et al. 2022. Cancer Cell. 40:36. PubMed
  16. Koenig A, et al. 2022. Front Immunol. 12:791100. PubMed
  17. Zhu M, et al. 2022. Front Immunol. 13:1019248. PubMed
  18. Briukhovetska D, et al. 2023. Immunity. 56:143. PubMed
  19. Zhang J, et al. 2023. Int J Nanomedicine. 18:209. PubMed
  20. Elliot TAE, et al. 2022. Discov Immunol. 1:kyac009. PubMed
  21. Schick J, et al. 2023. Elife. 12: . PubMed
  22. Shirai T, et al. 2022. Cancer Sci. 113:3710. PubMed
  23. Giampaolo S, et al. 2023. iScience. 26:106234. PubMed
  24. Do-Thi VA, et al. 2023. Cancer Res Commun. 3:80. PubMed
  25. Kondo H, et al. 2020. J Biol Chem. 295:1658. PubMed
  26. Wan Mohd Zawawi WFA, et al. 2021. Sci Rep. 11:10278. PubMed
  27. Boyd DF, et al. 2020. Nature. 587:466. PubMed
  28. Krovi SH, et al. 2019. Proc Natl Acad Sci U S A. 116:22252. PubMed
  29. Biljes D, et al. 2017. EXCLI J. 0.86875. PubMed
  30. Chartrand K, et al. 2018. Front Immunol. 1.642361111. PubMed
  31. Goel S, et al. 2017. Nature. 548:471. PubMed
  32. Field CS, et al. 2018. Oncoimmunology. 7:e1376154. PubMed
  33. Namavari A, et al. 2012. Invest Ophthalmol Vis Sci . 53:4575. PubMed
  34. Uzhachenko RV, et al. 2021. Cell Reports. 35(1):108944. PubMed
  35. Prado C, et al. 2021. J Neuroinflammation. 18:292. PubMed
  36. Liang W, et al. 2022. Methods Mol Biol. 2574:221. PubMed
  37. Nagatake T, et al. 2022. Mucosal Immunol. 15:289. PubMed
  38. McLane LM, et al. 2021. Cell Reports. 35(6):109120. PubMed
  39. Chen L, et al. 2019. Nat Commun. 3.553472222. PubMed
  40. Sanctuary MR, et al. 2019. Mucosal Immunol. 0.638888889. PubMed
  41. Carpenter SM, et al. 2017. PLoS Pathog. 13:e1006704. PubMed
  42. Wong E, et al. 2019. Cell Rep. 29:3047. PubMed
  43. Crawford G, et al. 2018. Nat Immunol. 1.388194444. PubMed
  44. Cao Q, et al. 2018. Am J Physiol Renal Physiol. 314:F561. PubMed
  45. Oghumu S, et al. 2019. J Immunol. 203:789. PubMed
  46. Arimura K, et al. 2017. Mucosal Immunol. 1.08125. PubMed
  47. Zhou AC, et al. 2017. Front Immunol. 1.136111111. PubMed
  48. Niss Arfelt K, et al. 2017. Blood. 129:866. PubMed
  49. Jennings EK, et al. 2021. STAR Protocols. 2(1):100284. PubMed
  50. Lu SX, et al. 2021. Cell. . PubMed
  51. Liu W, et al. 2021. Stem Cell Res Ther. 12:153. PubMed
  52. Joseph R, et al. 2021. Br J Cancer. 125:176. PubMed
  53. Willimsky G, et al. 2021. Elife. 10:. PubMed
  54. Quintana E, et al. 2020. Cancer Res. 80:2889. PubMed
  55. Delgobo M, et al. 2021. Front Immunol. 12:584538. PubMed
  56. Peng V, et al. 2020. J Biol Chem. 295:14866. PubMed
  57. Tanaka Y, et al. 2021. Int J Mol Sci. 22:. PubMed
  58. Muhammad F, et al. 2020. Front Immunol. 975:11. PubMed
  59. Yi M, et al. 2021. J Hematol Oncol. 14:27. PubMed
  60. Edenborough KM, et al. 2019. Front Immunol. 10:2414. PubMed
  61. McLeod RL, et al. 2018. Oncotarget. 9:34459. PubMed
  62. Robert S, et al. 2018. Bone Marrow Transplant. 53:807. PubMed
  63. Morabito KM, et al. 2017. Mucosal Immunol. 0.795138889. PubMed
  64. Rissiek B, et al. 2017. Sci Rep. . 10.1038/s41598-017-16613-w. PubMed
  65. Sekiya T et al. 2018. Cell reports. 24(6):1627-1638 . PubMed
  66. Lyon de Ana C, et al. 2019. J Immunol. 202:1112. PubMed
  67. Wu P et al. 2019. Molecular cell. 73(5):1015-1027 . PubMed
  68. Tuzlak S, et al. 2017. Cell Death Differ. 24:523. PubMed
  69. Doorduijn EM, et al. 2018. Front Immunol. 0.416666667. PubMed
  70. Rao TN, et al. 2020. J Immunol. 204:2600. PubMed
  71. Perchonock C, et al. 2006. Mol Cell Biol . 26:6005. PubMed
  72. Guo Y, et al. 2008. Blood. 112:480. PubMed
  73. El Maï M, et al. 2021. Cancers (Basel). 13:. PubMed
  74. Baluk P, et al. 2020. Am J Pathol. 190:2355. PubMed
  75. Mullins GN, et al. 2020. Sci Rep. 10:21994. PubMed
  76. Hilligan KL, et al. 2020. Nat Commun. 11:5637. PubMed
  77. Suzuki Y, et al. 2021. FEBS Open Bio. 11:2619. PubMed
  78. Zhang P, et al. 2022. BMC Med. 20:435. PubMed
  79. Hanoteau A, et al. 2019. J Immunother Cancer. 7:10. PubMed
  80. Stacey MA, et al. 2017. J Clin Invest. 127:1463. PubMed
  81. Duc D et al. 2019. Cell Rep. 29(2):378-390 . PubMed
  82. Xu L et al. 2017. Immunity. 47(3):538-551 . PubMed
  83. Chen Z et al. 2019. Immunity. 51(5):840-855 . PubMed
  84. Gartlan KH, et al. 2019. Blood Adv. 2.110416667. PubMed
  85. Abboud G, et al. 2018. Front Immunol. 9:1973. PubMed
  86. McCully M, et al. 2015. J Immunol. 195: 96 - 104. PubMed
  87. Bremser A, et al. 2015. PLoS One. 10: 0137393. PubMed
  88. Cain MP, et al. 2020. Dis Model Mech. 13:00. PubMed
  89. Takushi SE, et al. 2020. Hum Gene Ther. 31:626. PubMed
  90. Imani J, et al. 2021. JCI Insight. 6:. PubMed
  91. Xie D, et al. 2020. Eur J Immunol. 50:1729. PubMed
  92. Reed J, et al. 2020. Bio Protoc. 10:e3607. PubMed
  93. Morales-Mantilla DE, et al. 2022. Elife. 11:. PubMed
  94. Brown IK, et al. 2021. PLoS Pathog. 17:e1009602. PubMed
  95. Di Martino L, et al. 2021. Cell Mol Gastroenterol Hepatol. 13:901. PubMed
  96. James OJ, et al. 2021. Nat Commun. 12:4290. PubMed
  97. Borges TJ, et al. 2018. Nat Commun. 9:3482. PubMed
  98. Won HY, et al. 2017. Sci Rep. 7:16946. PubMed
  99. Van De Velde LA, et al. 2017. J Biol Chem. 292:15:00. PubMed
  100. Scholz T, et al. 2017. PLoS One. 12:e0182646. PubMed
  101. Sprouse ML, et al. 2018. JCI Insight. 3:e97322. PubMed
  102. Lee JY, et al. 2018. Front Immunol. 0.678472222. PubMed
  103. Sharabi A, et al. 2019. JCI Insight. 4:e126294. PubMed
  104. Du J, et al. 2018. AMB Express. 8:158. PubMed
  105. Majer O, et al. 2019. Nature. 575:366. PubMed
  106. Hsieh WC, et al. 2020. JCI Insight. 5:00. PubMed
  107. Sharma M, et al. 2020. Circ Res. 127:335. PubMed
  108. Sun L, et al. 2022. Front Immunol. 13:823853. PubMed
  109. Wu G, et al. 2022. Wellcome Open Res. 6:134. PubMed
  110. Otsuka S, et al. 2021. J Clin Invest. 131:. PubMed
  111. Schuler CF, et al. 2020. Allergy. 75:2279. PubMed
  112. Yoon S, et al. 2020. Antioxidants (Basel). 10:. PubMed
  113. Tao H, et al. 2021. Front Immunol. 12:623280. PubMed
  114. Ma VP, et al. 2022. Sci Adv. 8:eabg4485. PubMed
  115. Li Z, et al. 2021. MBio. 12:e0254221. PubMed
  116. Ejima R, et al. 2021. Nutrients. 13:. PubMed
  117. Becker W, et al. 2021. J Crohns Colitis. 15:1032. PubMed
  118. Chen HW, et al. 2021. Biomedicines. 9:. PubMed
  119. Seo N, et al. 2018. Nat Commun. 9:435. PubMed
  120. Parzmair GP, et al. 2017. J Leukoc Biol. 101:407. PubMed
  121. Kälin S et al. 2017. Cell metabolism. 26(3):475-492 . PubMed
  122. Simula L et al. 2018. Cell reports. 25(11):3059-3073 . PubMed
  123. Nagatake T, et al. 2018. Int Immunol. 30:471. PubMed
  124. Hao Y, et al. 2018. Front Immunol. 9:1127. PubMed
  125. Baluk P, et al. 2018. Methods Mol Biol. 1846:161. PubMed
  126. Katagiri T, et al. 2019. Mucosal Immunol. 12:p1104. PubMed
  127. Wang HC, et al. 2017. J Immunol. 198:3149. PubMed
  128. Parigi SM, et al. 2018. Sci Rep. 0.440277778. PubMed
  129. Klein JC, et al. 2017. Nat Commun. 8:14600. PubMed
  130. Sandy A, et al. 2013. J Immunol. 190:5818. PubMed
  131. Sripada A, et al. 2021. PLoS Biol. 19:e3001063. PubMed
  132. Shiozawa S, et al. 2022. iScience. 25:103537. PubMed
  133. Wu Y, et al. 2021. J Clin Invest. 131:. PubMed
  134. Rigo MM, et al. 2020. FEBS J. :. PubMed
  135. Lee J, et al. 2020. Cells. 9:. PubMed
  136. Seo SU, et al. 2021. Front Immunol. 12:697162. PubMed
  137. Goh W, et al. 2020. Cell Rep. 33:108285. PubMed
  138. Spranger S, et al. 2017. Cancer Cell. 31:711. PubMed
  139. Wang W, et al. 2018. J Vasc Surg. 68:1538. PubMed
  140. Nagatake T, et al. 2018. J Allergy Clin Immunol. 142:470. PubMed
  141. Link MA, et al. 2017. PLoS One. 12:e0184320. PubMed
  142. Teijeira A, et al. 2018. Cancer Immunol Res. 6:798. PubMed
  143. Jiao S, et al. 2020. Cell. 179(5):1177-1190.e13.. PubMed
  144. Fernández-Orth J, et al. 2020. Eur J Immunol. . PubMed
  145. Aguilar OA, et al. 2020. J Immunol. 205:1709. PubMed
  146. Taylor MD, et al. 2020. Front Immunol. 11:1946. PubMed
  147. Kissiov DU, et al. 2022. Elife. 11:. PubMed
  148. Yoon S, et al. 2022. Nat Commun. 13:1602. PubMed
  149. Koch K, et al. 2022. Int J Mol Sci. 23:. PubMed
  150. Yang H, et al. 2022. Cell Death Discov. 8:183. PubMed
  151. Qiu Z, et al. 2022. Cancer Discov. 12:502. PubMed
  152. Sun Y, et al. 2021. Nat Commun. 12:5147. PubMed
  153. Lin Z, et al. 2021. Stem Cells. 39:240. PubMed
  154. Chen Z, et al. 2021. Cell. 184(5):1262-1280.e22. PubMed
  155. Gaspar M, et al. 2020. Cancer Immunol Res. 0.875694444. PubMed
  156. Wagner AK, et al. 2017. Nat Commun. 8:15627. PubMed
  157. Stelekati E, et al. 2018. Cell Rep. 2.445833333. PubMed
  158. Cui X, et al. 2017. J Immunol. 199:4066. PubMed
  159. Simmons S et al. 2019. Elife. 8 pii: e41239. PubMed
  160. Niven J, et al. 2019. Cell Rep. 28:21. PubMed
  161. Coley WD et al. 2018. F1000Research. 2018 Mar 14 [revised 2018 Jan 1] 0.5125. PubMed
  162. Gaya M et al. 2018. Cell. 172(3):517-533 . PubMed
  163. Afzali B, et al. 2017. Nat Immunol. 18:813. PubMed
  164. Cohen MA, et al. 2020. Cell Stem Cell. 26(4):579-592. PubMed
  165. Genoud V, et al. 2018. Oncoimmunology. 7:e1501137. PubMed
  166. Dey P, et al. 2020. Cancer Discov. 10:608. PubMed
  167. Schnoegl D, et al. 2022. Front Immunol. 13:909270. PubMed
  168. Taylor MD, et al. 2020. Front Immunol. 11:563402. PubMed
  169. Nagatake T, et al. 2021. Int Immunol. 33:171. PubMed
  170. Sasai M, et al. 2021. J Exp Med. 218:. PubMed
  171. Perchonock C, et al. 2007. J Immunol. 179:1768. PubMed
  172. Cole C, et al. 2018. Nucleic Acids Res. 46:e62. PubMed
  173. Abe Y, et al. 2017. Biochem Biophys Rep. 0.543055556. PubMed
  174. Nakamura K, et al. 2018. Cancer Cell. 33:634. PubMed
  175. Lin J, et al. 2017. Nat Commun. . 10.1038/s41467-017-01477-5. PubMed
  176. An Y et al. 2018. Cell reports. 25(3):702-714 . PubMed
  177. Kikuchi K, et al. 2018. J Immunol. 201:635. PubMed
  178. Akkaya B, et al. 2018. J Immunol. 201:3294. PubMed
  179. Khameneh HJ, et al. 2017. J Immunol. 198:196. PubMed
  180. Wang N, et al. 2020. Front Immunol. 1.765972222. PubMed
  181. Wang G, et al. 2015. PLoS One. 10:121968. PubMed
  182. Kojima T, et al. 2016. Sci Rep. 6:36457. PubMed
  183. Katsuyama T, et al. 2021. Cell Reports. 36(1):109339. PubMed
  184. Kästle M, et al. 2020. Cell Commun Signal. 183:18. PubMed
  185. Bordoloi D, et al. 2021. Genes Cancer. 12:51. PubMed
  186. Wang W, et al. 2022. Nat Commun. 13:4495. PubMed
  187. Umeda M, et al. 2021. Proc Natl Acad Sci U S A. 118:. PubMed
  188. Prabakaran T, et al. 2021. EBioMedicine. 66:103314. PubMed
  189. Yamazaki K, et al. 2022. Sci Rep. 12:3242. PubMed
  190. Chen YH, et al. 2022. Arthritis Res Ther. 24:27. PubMed
  191. Sutiwisesak R, et al. 2020. PLoS Pathog. 16:e1009000. PubMed
  192. Xia L, et al. 2021. Cancer Immunol Res. 9:707. PubMed
  193. Galeano Nio JL, et al. 2020. eLife. 9:00. PubMed
  194. Fritz Y, et al. 2017. J Invest Dermatol. 137:696. PubMed
RRID
AB_312666 (BioLegend Cat. No. 100301)
AB_312666 (BioLegend Cat. No. 100302)

Antigen Details

Structure
Ig superfamily, forms CD3/TCR complex with CD3δ, γ and ζ subunits and TCR (α/β and γ/δ), 20 kD
Distribution

Thymocytes (differentiation dependent), mature T cells, NK-T cells

Function
TCR signal transduction, T cell activation, antigen recognition
Ligand/Receptor
Peptide antigen/MHC-complex
Cell Type
NKT cells, T cells, Thymocytes, Tregs
Biology Area
Immunology
Molecular Family
CD Molecules, TCRs
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Davis MM. 1990. Annu. Rev. Biochem. 59:475.
3. Weiss A, et al. 1994. Cell 76:263.

Gene ID
12501 View all products for this Gene ID
UniProt
View information about CD3epsilon on UniProt.org

Related FAQs

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Go To Top Version: 2    Revision Date: 10.17.2017

For Research Use Only. Not for diagnostic or therapeutic use.

 

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Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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