- Clone
- 5G11 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- LTbR, TNFRIII, TNF receptor-related protein (TNFRrp)
- Isotype
- Rat IgG2a, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
134402 | 100 µg | 188€ |
LTβR is a type I transmembrane glycoprotein and member of the TNF receptor superfamily. It is a 61 KDa receptor for the mouse LTα1β2 and LIGHT. Northern blot analysis of tissues from adult mice showed that expression levels of LTβR mRNA were strong in lung, liver, and kidney, moderate in heart and testes, but weak in brain, thymus, spleen, and lymph nodes. It was reported that LTβR is expressed on stromal cells, monocytes, and certain embryonic epithelial layers. LTβR is involved in peripheral lymphoid tissue organogenesis and function. The LTα/LTβR receptor system may also have some function in early embryogenesis.
Product DetailsProduct Details
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- E.coli expressed extracellular domain of mouse lymphotoxin beta receptor
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Product Citations
-
- RRID
-
AB_1659177 (BioLegend Cat. No. 134402)
Antigen Details
- Distribution
-
Expressed on stromal cells, monocytes, and certain embryonic epithelial layers.
- Function
- LTβR is involved in peripheral lymphoid tissue organogenesis and function. The LTα/LTβR receptor system may also have some function in early embryogenesis.
- Ligand/Receptor
- LTα1β2 and LIGHT
- Cell Type
- Embryonic Stem Cells, Epithelial cells, Monocytes
- Biology Area
- Immunology, Stem Cells
- Molecular Family
- Adhesion Molecules, Cytokine/Chemokine Receptors
- Antigen References
-
1. Force WR, et al. 1995. J. Immunol. 155:5280
2. Tamada K, et al. 2000. J. Immunol. 164:4105
3. Browing JL, et al. 1997. J. Immunol. 159:3288
4. Futterer A, et al. 1998. Immunity 9:59
5. Nakamura T, et al. 1995. Genomics 30:312
6. Crowe P, et al. 1996. Science 264:707
7. Dejardin E, et al. Immunity 2002. 17(4):525 - Gene ID
- 17000 View all products for this Gene ID
- UniProt
- View information about LT-betaR on UniProt.org
Related Pages & Pathways
Pages
Other Formats
View All LT-βR Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-mouse lymphotoxin beta receptor (LTβR) | 5G11 | FC |
PE anti-mouse lymphotoxin beta receptor (LTβR) | 5G11 | FC |
PE/Cyanine7 anti-mouse lymphotoxin beta receptor (LTβR) | 5G11 | FC |
APC anti-mouse lymphotoxin beta receptor (LTβR) | 5G11 | FC |
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