Purified anti-mouse TCR Vβ13 Recombinant Antibody

Pricing & Availability
Clone
QA19A88 (See other available formats)
Regulatory Status
RUO
Isotype
Mouse IgG1, κ
Ave. Rating
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Product Citations
publications
QA19A88_PURE_TCRVbeta13_Antibody_2_02032022
C57BL/6 mouse splenocytes were stained with anti-mouse CD3 FITC and purified anti-mouse TCR Vβ13 recombinant (clone QA19A88) (left) or purified mouse IgG1, κ isotype control (right) followed by anti-mouse IgG1 PE.
  • QA19A88_PURE_TCRVbeta13_Antibody_2_02032022
    C57BL/6 mouse splenocytes were stained with anti-mouse CD3 FITC and purified anti-mouse TCR Vβ13 recombinant (clone QA19A88) (left) or purified mouse IgG1, κ isotype control (right) followed by anti-mouse IgG1 PE.
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104202 100 µg 90€
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Description

Vβ13 T cell receptor (TCR Vβ13) is a variant of TCR β chain that along with TCR α chain forms the TCR heterodimer. In association with the CD3 complex, TCR α/β is responsible for antigen recognition in the MHC-Peptide complex and initiation of T cell-mediated immune responses. The most frequently β chains found in the immune response to myelin basic protein (MBP) in B10.PL mice are Vβ13 and Vβ8.2.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Recombinant
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.

RRID
AB_2922455 (BioLegend Cat. No. 104202)

Antigen Details

Structure
Member of the immunoglobulin superfamily, Vβ13 is a variant of the TCR β chain which associates with the TCR α chain to form the TCR heterodimer
Distribution

Expressed on a subset of TCR αβ+ T cells

Function
Recognition of peptides presented by the MHC molecules, responsible for T cell mediated immune responses
Ligand/Receptor
MHC-Peptide complex
Cell Type
T cells, Th1, Th17
Biology Area
Immunology
Molecular Family
TCRs
Antigen References
  1. Zaller DM, et al. 1990. J Exp Med. 171:1943-55.
  2. Gentile F, et al. 2004. Immunology. 112:13-25.
  3. Lode HN, et al. 1999. Proc Natl Acad Sci U S A. 96:8591-6.
Gene ID
21577 View all products for this Gene ID
UniProt
View information about TCR Vbeta13 on UniProt.org

Related FAQs

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Go To Top Version: 1    Revision Date: 02.03.2022

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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