- Clone
- S15049I (See other available formats)
- Regulatory Status
- RUO
- Other Names
- M130, MM130, SCARI1
- Isotype
- Rat IgG2a, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
155329 | 25 µg | 112€ | ||||
155330 | 100 µg | 280€ |
CD163 is a member of the group B scavenger receptor cysteine-rich superfamily, also known as GHI/61, M130, RM3/1, p155, hemoglobin-haptoglobin complex receptor, or macrophage-associated antigen. It is a 134 kD (non-reduced)/155 kD (reduced) glycoprotein primarily expressed on macrophages, Kupffer cells, monocytes, a subset of dendritic cells, and a subset of hematopoietic stem/progenitor cells. CD163 binds to haptoglobin-hemoglobin complex and TWEAK, and plays a role in clearing hemoglobin and regulating cytokine production by macrophages. Membrane CD163 can be cleaved by metalloproteinases (MMP), resulting in a soluble form. Elevated serum level of sCD163 has been implicated in many kinds of inflammatory diseases.
Product DetailsProduct Details
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Recombinant mouse CD163 extracellular domain
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
* Alexa Fluor® 647 has a maximum emission of 668 nm when it is excited at 633 nm / 635 nm.
Alexa Fluor® and Pacific Blue™ are trademarks of Life Technologies Corporation.
View full statement regarding label licenses - Excitation Laser
-
Red Laser (633 nm)
- RRID
-
AB_3097365 (BioLegend Cat. No. 155329)
AB_3097365 (BioLegend Cat. No. 155330)
Antigen Details
- Structure
- Type 1 transmembrane glycoprotein, 134 kD (non-reduced)/155 kD (reduced) glycoprotein
- Distribution
-
Macrophages, Kupffer cells, monocytes, a subset of dendritic cells, and a subset of hematopoietic stem/progenitor cells
- Function
- Binds to haptoglobin-hemoglobin complex and TWEAK, and plays a role in clearing hemoglobin and regulating cytokine production by macrophages
- Biology Area
- Immunology
- Molecular Family
- CD Molecules
- Gene ID
- 93671 View all products for this Gene ID
- UniProt
- View information about CD163 on UniProt.org
Related Pages & Pathways
Pages
Other Formats
View All CD163 Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-mouse CD163 | S15049I | FC,IHC-F |
Brilliant Violet 421™ anti-mouse CD163 | S15049I | FC |
PE anti-mouse CD163 | S15049I | FC |
APC anti-mouse CD163 | S15049I | FC |
TotalSeq™-A0417 anti-mouse CD163 | S15049I | PG |
TotalSeq™-B0417 anti-mouse CD163 | S15049I | PG |
TotalSeq™-C0417 anti-mouse CD163 | S15049I | PG |
PE/Dazzle™ 594 anti-mouse CD163 Antibody | S15049I | FC |
KIRAVIA Blue 520™ anti-mouse CD163 Antibody | S15049I | FC |
PE/Cyanine7 anti-mouse CD163 Antibody | S15049I | FC |
APC/Fire™ 810 anti-mouse CD163 Antibody | S15049I | FC |
APC/Cyanine7 anti-mouse CD163 | S15049I | FC |
Brilliant Violet 711™ anti-mouse CD163 | S15049I | FC |
Brilliant Violet 605™ anti-mouse CD163 | S15049I | FC |
Alexa Fluor® 647 anti-mouse CD163 | S15049I | FC |
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Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
-
Purified anti-mouse CD163
C57BL/6 mouse peritoneal macrophages were cultured for seven... C57BL/6 bone marrow were stained with CD11b APC and purified... C57BL/6 mouse frozen spleen section was fixed with 4% parafo... C57BL/6 mouse frozen liver section was fixed with 4% parafor... -
Brilliant Violet 421™ anti-mouse CD163
C57BL/6 bone marrow were stained with CD11b APC and CD163 Br... -
PE anti-mouse CD163
C57BL/6 bone marrow were stained with CD11b APC and CD163 (c... -
APC anti-mouse CD163
C57BL/6 bone marrow cells were stained with CD11b PE and CD1... -
TotalSeq™-A0417 anti-mouse CD163
-
TotalSeq™-B0417 anti-mouse CD163
-
TotalSeq™-C0417 anti-mouse CD163
-
PE/Dazzle™ 594 anti-mouse CD163 Antibody
C57BL/6 mouse bone marrow cells were stained with CD11b APC ... -
KIRAVIA Blue 520™ anti-mouse CD163 Antibody
C57BL/6 mouse bone marrow cells were stained with CD11b APC ... -
PE/Cyanine7 anti-mouse CD163 Antibody
C57BL/6 mouse bone marrow cells were stained with CD11b APC ... -
APC/Fire™ 810 anti-mouse CD163 Antibody
C57BL/6 mouse bone marrow cells were stained with anti-mouse... -
APC/Cyanine7 anti-mouse CD163
C57BL/6 mouse bone marrow cells were stained with anti-mouse... -
Brilliant Violet 711™ anti-mouse CD163
C57BL/6 mouse bone marrow were stained with anti-mouse CD11b... -
Brilliant Violet 605™ anti-mouse CD163
C57BL/6 bone marrow cells were stained with anti-mouse CD11b... -
Alexa Fluor® 647 anti-mouse CD163
C57BL/6 bone marrow cells were stained with anti-mouse CD11b...
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