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APC anti-human MUC-17 Antibody

Pricing & Availability
Clone
MQ155 (See other available formats)
Regulatory Status
RUO
Other Names
Mucin-17, MUC3, MUC-3
Isotype
Mouse IgG1, κ
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Product Citations
publications
MQ155_APC_MUC-17_Antibody_103020
Human pancreatic cancer cell line (AsPC-1) was stained with anti-human MUC-17 (clone MQ155) APC (filled histogram) or mouse IgG1, κ APC isotype control.
  • MQ155_APC_MUC-17_Antibody_103020
    Human pancreatic cancer cell line (AsPC-1) was stained with anti-human MUC-17 (clone MQ155) APC (filled histogram) or mouse IgG1, κ APC isotype control.
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395305 25 tests 120€
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395306 100 tests 313€
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Description

It is a 451 KD glycocylated member of the mucin family with 2 EGF like domains on the C-terminus and serine/tyrosine phosphorylation sites on the cytoplasmic domain. It is expressed by epithelial cells and plays a role in cytoprotection, signal transduction. Expression of this molecule can also render tumor cells to become less adhesive. It interacts with PKDZ1 and increased expression of this molecule has been reported in colon cancer.

Product Details
Technical data sheet

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Purified recombinant Muc17 protein, Freund’s Complete Adjuvant
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Red Laser (633 nm)
RRID
AB_2888814 (BioLegend Cat. No. 395305)
AB_2888814 (BioLegend Cat. No. 395306)

Antigen Details

Structure
451 KD N-glycosylate single pass membrane protein
Distribution

Gastrointestinal tract

Function
Cytoprotection, extravasation, signal transduction
Interaction
PDZK1
Biology Area
Cancer Biomarkers, Cell Biology, Cell Motility/Cytoskeleton/Structure, Immunology, Innate Immunity
Antigen References
  1. Malmberg EK, et al. 2008. Biochem J. 410:283.
  2. Gum JR Jr, et al. 2002. Biochem Biophys Res Commun. 291:466.
  3. Hirono S, et al. 2010. Cancer Sci. 101:259.
Gene ID
140453 View all products for this Gene ID
UniProt
View information about MUC-17 on UniProt.org
Go To Top Version: 1    Revision Date: 10.30.2020

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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