- Clone
- SA214G2 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- CDw198, C-C chemokine receptor type 8, CKR-8, CC-CKR-8, Ter1
- Isotype
- Rat IgG2b, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
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150339 | 50 µg | 216€ |
C-C chemokine receptor type 8 (CCR8) CD198, is a 41 kD G-protein coupled receptor with 7 transmembrane regions. CCR8 is expressed by a subset of thymocytes, Tregs, NKT and Th2-polarized cells, a subset of macrophages, monocytes, and monocyte-derived dendritic cells. CCR8 mediates chemotaxis toward its ligand CCL1, and is involved in apoptosis of thymocytes.
Product DetailsProduct Details
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Mouse CD198 (CCR8)-transfected cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with Brilliant Violet 605™ under optimal conditions.
- Concentration
- 0.2 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
Brilliant Violet 605™ excites at 405 nm and emits at 603 nm. The bandpass filter 610/20 nm is recommended for detection, although filter optimization may be required depending on other fluorophores used. Be sure to verify that your cytometer configuration and software setup are appropriate for detecting this channel. Refer to your instrument manual or manufacturer for support. Brilliant Violet 605™ is a trademark of Sirigen Group Ltd.
Learn more about Brilliant Violet™.
This product is subject to proprietary rights of Sirigen Inc. and is made and sold under license from Sirigen Inc. The purchase of this product conveys to the buyer a non-transferable right to use the purchased product for research purposes only. This product may not be resold or incorporated in any manner into another product for resale. Any use for therapeutics or diagnostics is strictly prohibited. This product is covered by U.S. Patent(s), pending patent applications and foreign equivalents. - Excitation Laser
-
Violet Laser (405 nm)
- RRID
-
AB_3068123 (BioLegend Cat. No. 150339)
Antigen Details
- Structure
- G-protein coupled receptor, 7 transmembrane regions, 41 kD.
- Distribution
-
Thymocytes, Tregs, NKT and Th2-polarized cells, subset of macrophages, monocytes and monocyte-derived dendritic cells.
- Function
- Chemotaxis, involved in thymocyte apoptosis
- Ligand/Receptor
- CCL1 (SCY1,TCA-3)
- Cell Type
- Dendritic cells, Macrophages, Monocytes, NKT cells, Th2, Thymocytes, Tregs
- Biology Area
- Immunology
- Molecular Family
- CD Molecules, Cytokine/Chemokine Receptors, GPCR
- Antigen References
-
1. Coghill JM, et al. 2013. Blood. 122:825.
2. Islam SA, et al. 2011. Nat. Immunol. 12:167.
3. Hoshino A, et al. 2007. J. Immunol. 178:5296.
3. Qu C, et al. 2004. J. Exp. Med. 200:1231. - Gene ID
- 12776 View all products for this Gene ID
- UniProt
- View information about CD198 on UniProt.org
Related Pages & Pathways
Pages
Related FAQs
Other Formats
View All CD198 Reagents Request Custom ConjugationCompare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-mouse CD198 (CCR8)
C57BL/6 mouse thymocytes were stained with purified CCR8 (cl... Murine T-cell lymphoma cell line BW5147.3 was stained with p... -
Alexa Fluor® 647 anti-mouse CD198 (CCR8)
C57BL/6 mouse thymocytes were stained with CD4 FITC and CCR8... -
PerCP/Cyanine5.5 anti-mouse CD198 (CCR8)
C57BL/6 mouse thymocytes were stained with CD4 APC and CD198... -
Brilliant Violet 421™ anti-mouse CD198 (CCR8)
C57BL/6 mouse thymocytes were stained with CD4 FITC and CCR8... -
PE anti-mouse CD198 (CCR8)
C57BL/6 mouse thymocytes were stained with CD4 APC and CCR8 ... -
FITC anti-mouse CD198 (CCR8)
C57BL/6 mouse thymocytes were stained with CD4 APC and CCR8 ... -
APC anti-mouse CD198 (CCR8)
C57BL/6 mouse thymocytes were stained with CD4 FITC and CD19... -
Biotin anti-mouse CD198 (CCR8)
C57BL/6 mouse thymocytes were stained with CD4 APC and CCR8 ... -
APC/Fire™ 750 anti-mouse CD198 (CCR8)
C57BL/6 mouse thymocytes were stained with CD4 PE and CD198 ... -
Brilliant Violet 711™ anti-mouse CD198 (CCR8)
C57BL/6 mouse thymocytes were stained with CD4 PE and CD198 ... -
TotalSeq™-C0907 anti-mouse CD198 (CCR8)
-
Alexa Fluor® 488 anti-mouse CD198 (CCR8) Antibody
C57BL/6 mouse thymocytes were stained with CD4 APC and anti-... -
KIRAVIA Blue 520™ anti-mouse CD198 (CCR8) Antibody
C57BL/6 mouse thymocytes were stained with CD4 APC and anti-... -
PE/Dazzle™ 594 anti-mouse CD198 (CCR8) Antibody
C57BL/6 mouse thymocytes were stained with CD4 APC and anti-... -
TotalSeq™-B0907 anti-mouse CD198 (CCR8)
-
Spark NIR™ 685 anti-mouse CD198 (CCR8)
C57BL/6 mouse thymocytes were stained with anti-mouse CD4 FI... -
Alexa Fluor® 700 anti-mouse CD198 (CCR8)
C57BL/6 mouse thymocytes were stained with anti-mouse CD4 FI... -
PE/Cyanine5 anti-mouse CD198 (CCR8)
C57BL/6 mouse thymocytes were stained with anti-mouse CD4 FI... -
TotalSeq™-A0907 anti-mouse CD198 (CCR8)
-
Ultra-LEAF™ Purified anti-mouse CD198 (CCR8)
C57BL/6 mouse thymocytes were stained with Ultra-LEAF™ purif... -
Brilliant Violet 605™ anti-mouse CD198 (CCR8)
C57BL/6 mouse thymocytes were stained with anti-mouse CD4 FI...
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