- Clone
- SA045E1 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- IL-8RB, GRO/MGSA, Cmkar2
- Isotype
- Rat IgG2a, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
149607 | 25 µg | 90€ | ||||
149608 | 100 µg | 203€ |
CD182, also known as CXCR2, is a G-protein coupled receptor with seven transmembrane regions that is involved in chemotaxis, neutrophil activation, and angiogenesis. CXCR2 is expressed by neutrophils, basophils, a subset of T cells, monocytes, macrophages, natural killer (NK) and natural killer T cells (NKT). Its ligands are CXCL1, CXCL2, CXCL3, and CXCL5.
Product DetailsProduct Details
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Mouse CXCR2-transfected cells.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with FITC under optimal conditions.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
-
Blue Laser (488 nm)
- Product Citations
-
- RRID
-
AB_2565687 (BioLegend Cat. No. 149607)
AB_2565687 (BioLegend Cat. No. 149608)
Antigen Details
- Structure
- G-protein coupled receptor and seven transmembrane regions.
- Distribution
-
Neutrophils, basophils, subset of T cells, monocytes, macrophages, and natural killer (NK) cells.
- Function
- Chemotaxis, neutrophil activation, and angiogenesis.
- Ligand/Receptor
- CXCL1, CXCL2, CXCL3, and CXCL5.
- Cell Type
- Basophils, Macrophages, Monocytes, Neutrophils, NK cells, T cells
- Biology Area
- Immunology, Innate Immunity
- Molecular Family
- CD Molecules, Cytokine/Chemokine Receptors, GPCR
- Antigen References
-
1. Spaan AN, et al. 2014. Nat. Commun. 5:5438.
2. Natsuaki Y, et al. 2014. Nat. Immunol. 15:1064.
3. Hsieh CY, et al. 2014. J. Immunol. 193:3693.
4. Diana J and Lehuen A. 2014. EMBO Mol. Med. 6:1090.
5. Stoolman JS, et al. 2014. J. Immunol. 193:564. - Gene ID
- 12765 View all products for this Gene ID
- UniProt
- View information about CD182 on UniProt.org
Related Pages & Pathways
Pages
Related FAQs
Other Formats
View All CD182 Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
FITC anti-mouse CD182 (CXCR2) | SA045E1 | FC |
Purified anti-mouse CD182 (CXCR2) | SA045E1 | FC |
Alexa Fluor® 647 anti-mouse CD182 (CXCR2) | SA045E1 | FC |
PerCP/Cyanine5.5 anti-mouse CD182 (CXCR2) | SA045E1 | FC |
PE anti-mouse CD182 (CXCR2) | SA045E1 | FC |
Ultra-LEAF™ Purified anti-mouse CD182 (CXCR2) | SA045E1 | FC |
PE/Dazzle™ 594 anti-mouse CD182 (CXCR2) | SA045E1 | FC |
PE/Cyanine7 anti-mouse CD182 (CXCR2) | SA045E1 | FC |
APC anti-mouse CD182 (CXCR2) | SA045E1 | FC |
Biotin anti-mouse CD182 (CXCR2) | SA045E1 | FC |
Spark Red™ 718 anti-mouse CD182 (CXCR2) (Flexi-Fluor™) | SA045E1 | FC |
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Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
-
FITC anti-mouse CD182 (CXCR2)
C57BL/6 mouse bone marrow cells were stained with Ly-6G/Ly-6... -
Purified anti-mouse CD182 (CXCR2)
C57BL/6 mouse bone marrow cells were stained with purified C... -
Alexa Fluor® 647 anti-mouse CD182 (CXCR2)
C57BL/6 mouse bone marrow cells were costained with Ly-6G/Ly... -
PerCP/Cyanine5.5 anti-mouse CD182 (CXCR2)
C57BL/6 mouse bone marrow cells were costained with Ly-6G/Ly... -
PE anti-mouse CD182 (CXCR2)
C57BL/6 mouse bone marrow cells were stained with Ly-6G/Ly-6... -
Ultra-LEAF™ Purified anti-mouse CD182 (CXCR2)
C57BL/6 mouse bone marrow cells were stained with Ultra-LEAF... -
PE/Dazzle™ 594 anti-mouse CD182 (CXCR2)
C57BL/6 mouse bone marrow cells were stained with Ly-6G/Ly-6... -
PE/Cyanine7 anti-mouse CD182 (CXCR2)
C57BL/6 mouse bone marrow cells were stained with Ly-6G/Ly-6... -
APC anti-mouse CD182 (CXCR2)
C57BL/6 mouse bone marrow cells were stained with Ly-6G/Ly-6... -
Biotin anti-mouse CD182 (CXCR2)
C57BL/6 mouse bone marrow cells were stained with Ly-6G/Ly-6... -
Spark Red™ 718 anti-mouse CD182 (CXCR2) (Flexi-Fluor™)
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