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- Clone
- QA19A15 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- CD161, NKR-P1, CD161a/CD161b, NKR-P1a/KLRB1a
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
-
Rat splenocytes were stained with anti-rat CD3 APC and anti-rat CD161 recombinant (clone QA19A15) FITC (left) or mouse IgG1, κ FITC isotype control (right).
| Cat # | Size | Price | Quantity Check Availability | Save | ||
|---|---|---|---|---|---|---|
| 251103 | 25 µg | 64€ | ||||
| 251104 | 100 µg | 140€ | ||||
QA19A15 recombinant monoclonal antibody recognizes the rat killer cell lectin-like receptor subfamily B member1 protein, also known as CD161. CD161 is expressed on rat NK cells and T cell subpopulations, activated monocytes, and dendritic cells. CD161 molecules are C-type lectin-like receptors that can either activate (CD161a) or inhibit (CD161b) effector leucocyte responses, eg, cytotoxicity or cytokine production, against target cells which express C-type lectin-like related (Clr) molecules.
Product DetailsProduct Details
- Verified Reactivity
- Rat
- Antibody Type
- Recombinant
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography and conjugated with FITC under optimal conditions.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.125 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
-
Blue Laser (488 nm)
- RRID
-
AB_3097231 (BioLegend Cat. No. 251103)
AB_3097231 (BioLegend Cat. No. 251104)
Antigen Details
- Structure
- CD161 is a 233 amino acid ~60 kDa homodimers, type II single pass protein containing a single C-type lectin domain.
- Distribution
-
NK cells, subset of T cells, dendritic cells, activated monocytes.
- Function
- NKR-P1a is a NK cell-activating receptor; NKR-P1b is a NK cell-inhibitory receptor.
- Ligand/Receptor
- LLT1-ligand lectin like transcript 1; KLR-killer cell lectin like receptor.
- Cell Type
- Dendritic cells, Monocytes, NK cells, T cells
- Biology Area
- Cell Biology, Immunology, Innate Immunity, Signal Transduction
- Molecular Family
- CD Molecules
- Antigen References
-
- Chambers WH, et al. 1989. J Exp Med. 169:1373.
- Brink M, et al. 1990. J Exp Med. 171:197.
- Li J, et al. 2003. Int Immunol. 15:411.
- Gene ID
- 362443 View all products for this Gene ID
- UniProt
- View information about CD161 on UniProt.org
Related Pages & Pathways
Pathways
Other Formats
View All CD161 Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| Purified anti-rat CD161 Recombinant Antibody | QA19A15 | FC |
| FITC anti-rat CD161 Recombinant Antibody | QA19A15 | FC |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
-
Purified anti-rat CD161 Recombinant Antibody
Rat splenocytes were stained with purified anti-rat CD161 re... -
FITC anti-rat CD161 Recombinant Antibody
Rat splenocytes were stained with anti-rat CD3 APC and anti-...
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