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Pricing & Availability
Human IL-28RA transfected BW5178 cells stained with MHLICR2a PE.
See PE spectral data
Technical data sheet
- Clone
- MHLICR2a (See other available formats)
- Regulatory Status
- RUO
- Other Names
- IFNLR1, CRF-2-12, LICR2
- Isotype
- Mouse IgG2a, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
-
Human IL-28RA transfected BW5178 cells stained with MHLICR2a PE.
| Cat # | Size | Price | Quantity Check Availability | Save | ||
|---|---|---|---|---|---|---|
| 337803 | 25 tests | 117€ | ||||
| 337804 | 100 tests | 254€ | ||||
Description
The IL-28RA, also known as IFNLR1, CRF-2-12, and LICR2, is a 57kD single-pass type I membrane glycoprotein containing one fibronectin III domain. Widely expressed in many tissue types, IL-28RA and IL-10RB dimerize to form the class II cytokine receptor for IL-28A (IFNλ2), IL-28B (IFNλ1) and IL-29 (IFNλ3), also known as the type III interferons. Like type I interferons, the type III interferons have been shown to activate the Jak-STAT and MAPK signalling pathways and exhibit antiviral activity.
Product Details
Product Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
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FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
- Excitation Laser
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Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
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Application References
(PubMed link indicates BioLegend citation) -
- Dumoutier L, et al.. 2004. J. Bio. Chem. 279:32269
- Product Citations
-
- RRID
-
AB_2125219 (BioLegend Cat. No. 337803)
AB_2125219 (BioLegend Cat. No. 337804)
Antigen Details
- Structure
- Single-pass type I membrane glycoprotein, one fibronectin III domain, Class II cytokine receptor, 57kD
- Distribution
- Broad tissue distribution at low level
- Interaction
- Coreceptor with IL-10RB
- Ligand/Receptor
- IL-28A (IFNλ2), IL-28B (IFNλ1) and IL-29 (IFNλ3)
- Biology Area
- Immunology
- Molecular Family
- Cytokine/Chemokine Receptors
- Antigen References
-
1. Renauld et al. J. Nature reviews Imm. 2003 3:667.
2. Sheppard P et al. Nature Imm. 2003 4:63.
3. Zhou Z et al. J. Virol. 2007 81:7749. - Gene ID
- 163702 View all products for this Gene ID
- UniProt
- View information about IL-28RA on UniProt.org
Related FAQs
- What type of PE do you use in your conjugates?
- We use R-PE in our conjugates.
Other Formats
View All IL-28RA Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| PE anti-human IL-28RA | MHLICR2a | FC |
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Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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PE anti-human IL-28RA
Human IL-28RA transfected BW5178 cells stained with MHLICR2a...
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