Purified anti-BG-4 Recombinant Antibody

Pricing & Availability
Clone
17-206.RecM1 (See other available formats)
Regulatory Status
RUO
Other Names
Blood group antigen H (type 1)
Isotype
Mouse IgG1, κ
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Product Citations
publications
17-206RecM1_PURE_BG-4_IHC-P_070824
IHC staining of Purified anti-BG-4 Recombinant (clone 17-206.RecM1) on formalin-fixed paraffin-embedded human antrum (stomach) tissue. The tissue was incubated with primary antibody overnight at 4°C. BioLegend’s Ultra Streptavidin HRP Kit (Multi-Species, DAB, Cat. No. 929501) was used for detection followed by hematoxylin counterstaining. The images were captured using a 10X (panel A) and 40X (panel B) objective. Scale bar: 50 µm
  • 17-206RecM1_PURE_BG-4_IHC-P_070824
    IHC staining of Purified anti-BG-4 Recombinant (clone 17-206.RecM1) on formalin-fixed paraffin-embedded human antrum (stomach) tissue. The tissue was incubated with primary antibody overnight at 4°C. BioLegend’s Ultra Streptavidin HRP Kit (Multi-Species, DAB, Cat. No. 929501) was used for detection followed by hematoxylin counterstaining. The images were captured using a 10X (panel A) and 40X (panel B) objective. Scale bar: 50 µm
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667551 25 µg 144€
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667552 100 µg 352€
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Description

BG-4, also known as blood group antigen H (type 1), is a carbohydrate sequence linked to a protein or ceramide. BG-4 is a precursor to the A and B antigens in the ABO system. For individuals with O type blood, the BG-4 antigen remains unmodified. BG-4 formation is catalyzed by the fucosyltransferase 1 enzyme (FUT1). BG-4 is expressed on erythrocytes and epithelial cells, and is thought to play a role in immune response, cell-cell recognition, and in the structural integrity of cells. 

Product Details
Technical data sheet

Product Details

Verified Reactivity
Human
Antibody Type
Recombinant
Host Species
Mouse
Immunogen
This antibody was developed against the SW-403 colon cancer cell line. It is specific for Blood group H (type 1).
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

IHC-P - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 1.0 - 10.0 µg/mL is suggested. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

With this antibody no antigen retrieval is required.

RRID
AB_3662334 (BioLegend Cat. No. 667551)
AB_3662334 (BioLegend Cat. No. 667552)

Antigen Details

Structure
BG-4 is a carbohydrate sequence consisting of a chain of β-D-galactose, β-D-N-acetylglucosamine, β-D-galactose, and 2-linked, α-L-fucose
Distribution

Cytoplasmic, cell surface

Function
Cell surface antigen, structural
Cell Type
Granulocytes, Macrophages, Monocytes, Neutrophils
Biology Area
Cell Biology, Immunology, Innate Immunity, Neuroinflammation, Neuroscience
Molecular Family
CD Molecules
Antigen References
  1. Lloyd KO, et al. 1983. Immunogen. 17:537.
  2. Sakamoto J, et al. 1984. Mol Immunol. 21:1093.
  3. Anger BR, et al. 1982. Hybridoma. 1:139.
Gene ID
NA
UniProt
View information about BG-4 on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 1    Revision Date: 07.09.2024

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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