- Clone
- LK26 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Folate receptor alpha, FR-alpha, KB cells FBP, folate binding protein, folate receptor, adult, adult folate-binding protein, ovarian tumor-associated antigen MOv18
- Previously
-
Signet Catalog# 619-01
Covance Catalog# SIG-3619
- Isotype
- Mouse IgG2a, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
908301 | 1 mL | 483€ |
Folate receptor (FOLR1), also known as folate receptor alpha, is a folate-binding protein (FBP) expressed in adults. It has high affinity for folic acid and its metabolites, including 5-methyltetrahydrofolate (5-MTF), the biologically active form of folic acid used for DNA synthesis and the cysteine cycle. FOLR1 mediates intracellular delivery of 5-MTF. FOLR1 is overexpressed in a variety of tumors, including breast, colorectal, and brain.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- This antibody was generated against gestational choriocarcinoma cell line, Lu-75 and detects folate-binding protein (FBP).
- Formulation
-
Phosphate-buffered solution with BSA + 0.09% NaN3.
Previous lots of this product may have been formulated with 0.1% or 0.05% NaN3 instead of 0.09% NaN3. For further information please contact BioLegend Technical Support or Customer Service. - Preparation
- The antibody was purified by affinity chromatography.
- Storage & Handling
- Store between 2°C and 8°C.
- Application
-
IHC-F - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunohistochemical staining on frozen tissue sections. For immunohistochemistry, a dilution of 1:40 is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
-
Application References
(PubMed link indicates BioLegend citation) -
- Hviid TV, et al. 1999. Prenat Diagn. 19: 271.
- Chesa-Garin P, et al. 1993. Am J Pathol. 142: 557.
- Rettig WJ, et al. 1985. Int J Cancer. 35:469.
- RRID
-
AB_2565084 (BioLegend Cat. No. 908301)
Antigen Details
- Structure
- The LK26 antigen is a 35-40 kD cell surface glycoprotein
- Gene ID
- 2348 View all products for this Gene ID
- UniProt
- View information about FOLR1 on UniProt.org
Related Pages & Pathways
Pages
Related FAQs
Other Formats
View All FOLR1 (Folate Binding Protein) Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-FOLR1 (Folate Binding Protein) | LK26 | IHC-F |
PE anti-FOLR1 (Folate Binding Protein) | LK26 | FC |
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Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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Purified anti-FOLR1 (Folate Binding Protein)
IHC staining of purified anti-FOLR1 (Folate Binding Protein)... -
PE anti-FOLR1 (Folate Binding Protein)
KB cells were stained with anti-FOLR1 (clone LK26) PE (close...
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