- Clone
- A10F1 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- HBsAg, Major surface protein, Large S protein, Hepatitis B Surface Antigen, ayw subtype, Australian antigen
- Isotype
- Mouse IgG2b, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
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932302 | 100 µg | 231€ |
Hepatitis B is a liver infection caused by the Hepatitis B virus (HBV). Hepatitis B surface antigen (HBsAg) contains the large (L), middle (M), and small (S) surface proteins of HBV. HBsAg can be detected at high levels in serum during acute or chronic HBV infection. The body normally produces antibodies to HBsAg as part of the normal immune response to infection. HBsAg is the antigen used to make the HBV vaccine and is also a diagnostic marker.
Product DetailsProduct Details
- Verified Reactivity
- Hepatatis B virus
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Purified HBsAg from human HBsAg-positive serum.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
IHC-P - Quality tested
WB - Reported in the literature, not verified in house - Recommended Usage
-
Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 1.0 - 5.0 µg/mL is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
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Application References
(PubMed link indicates BioLegend citation) -
- Huang T, et al. 2005. J. Biol. Chem. 280:27742. (WB)
- Wang H, et al. 2003. Am. J. Pathol. 163:2441. (WB)
- Shih H, et al. 2008. J. Virol. 82:2250. (WB)
- Shih H, et al. 2012. J. Virol. 86:9044. (WB)
- Hsu S, et al. 2004. J. Virol. 78:6. (WB)
- Product Citations
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- RRID
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AB_2566428 (BioLegend Cat. No. 932302)
Antigen Details
- Structure
- Hepatitis B surface antigen (HBsAg) contains the large (L), middle (M), and small (S) surface proteins of Hepatitis B virus (HBV).
- Distribution
-
HBsAg is on the surface of HBV that is present in bodily fluids and hepatocytes of infected individuals.
- Function
- HBsAg plays a key role in HBV's infection of hepatocytic cells.
- Interaction
- Hepatocytes.
- Ligand/Receptor
- Several hepatocytic receptors including asialoglycoprotein receptors and Annexin V.
- Biology Area
- Cell Biology
- Antigen References
-
1. Toita B, et al. 2015. World J. Gastroenterol. 24:7400-7411.
- Gene ID
- 944569 View all products for this Gene ID
- UniProt
- View information about HBsAg on UniProt.org
Related Pages & Pathways
Pages
Other Formats
View All HBsAg Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-Hepatitis B Surface Antigen (HBsAg) | A10F1 | IHC-P,WB |
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Purified anti-Hepatitis B Surface Antigen (HBsAg)
IHC staining of purified anti-Hepatitis B Surface Antigen (H...
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