- Clone
- HB-7 (See other available formats)
- Regulatory Status
- RUO
- Workshop
- III 155
- Other Names
- HB7, T10, ADP-ribosyl cyclase
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
356617 | 25 tests | £133 | ||||
356618 | 100 tests | £275 |
CD38 is a 45 kD type II transmembrane glycoprotein also known as T10. It is an ADP-ribosyl hydrolase expressed at variable levels on hematopoietic cells and in some non-hematopoietic tissues (such as brain, muscle, and kidney). In humans, it is expressed at high levels on plasma cells and activated T and B cells, natural killer (NK) lymphocytes, myeloblasts, and erythroblasts. By functioning as both a cyclase and a hydrolase, CD38 mediates lymphocyte activation, adhesion, and the metabolism of cADPR and NAADP. CD31 is the ligand of CD38.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- BJAB human B cell line.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA).
- Preparation
- The antibody was purified by affinity chromatography and conjugated with Brilliant Violet 421™ under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
Brilliant Violet 421™ excites at 405 nm and emits at 421 nm. The standard bandpass filter 450/50 nm is recommended for detection. Brilliant Violet 421™ is a trademark of Sirigen Group Ltd.
Learn more about Brilliant Violet™.
This product is subject to proprietary rights of Sirigen Inc. and is made and sold under license from Sirigen Inc. The purchase of this product conveys to the buyer a non-transferable right to use the purchased product for research purposes only. This product may not be resold or incorporated in any manner into another product for resale. Any use for therapeutics or diagnostics is strictly prohibited. This product is covered by U.S. Patent(s), pending patent applications and foreign equivalents. - Excitation Laser
-
Violet Laser (405 nm)
- Product Citations
-
- RRID
-
AB_2566230 (BioLegend Cat. No. 356617)
AB_2566230 (BioLegend Cat. No. 356618)
Antigen Details
- Structure
- ADP-ribosyl cyclase, ectoenzyme, type II glycoprotein, 45 kD
- Distribution
-
T cells, B cells, NK-cells, myeloid, plasma, and dendritic cells
- Function
- Ecto-ADP-ribosyl cyclase, calcium signaling, cell activation
- Ligand/Receptor
- CD31, hyaluronic acid
- Cell Type
- B cells, Dendritic cells, NK cells, Plasma cells, T cells
- Biology Area
- Cell Adhesion, Cell Biology, Immunology
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. Ferrero E, et al. 1999. J. Leukoc. Biol. 65:151.
2. Lund F, et al. 1995. Immunol. Today 16:469. - Gene ID
- 952 View all products for this Gene ID
- Specificity (DOES NOT SHOW ON TDS):
- CD38
- Specificity Alt (DOES NOT SHOW ON TDS):
- CD38
- App Abbreviation (DOES NOT SHOW ON TDS):
- FC
- UniProt
- View information about CD38 on UniProt.org
Related FAQs
- What is the F/P ratio range of our BV421™ format antibody reagents?
-
It is lot-specific. On average it ranges between 2-4.
Other Formats
View All CD38 Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-human CD38 | HB-7 | FC,ICC,WB |
PE anti-human CD38 | HB-7 | FC |
APC anti-human CD38 | HB-7 | FC |
PE/Cyanine7 anti-human CD38 | HB-7 | FC |
FITC anti-human CD38 | HB-7 | FC |
Brilliant Violet 510™ anti-human CD38 | HB-7 | FC |
PerCP/Cyanine5.5 anti-human CD38 | HB-7 | FC |
APC/Cyanine7 anti-human CD38 | HB-7 | FC |
Brilliant Violet 421™ anti-human CD38 | HB-7 | FC |
Brilliant Violet 650™ anti-human CD38 | HB-7 | FC |
PerCP anti-human CD38 | HB-7 | FC |
Alexa Fluor® 700 anti-human CD38 | HB-7 | FC |
APC/Fire™ 750 anti-human CD38 | HB-7 | FC |
Pacific Blue™ anti-human CD38 | HB-7 | FC |
PE/Dazzle™ 594 anti-human CD38 | HB-7 | FC |
Alexa Fluor® 647 anti-human CD38 | HB-7 | FC |
Alexa Fluor® 488 anti-human CD38 | HB-7 | FC |
TotalSeq™-A0410 anti-human CD38 | HB-7 | PG |
TotalSeq™-B0410 anti-human CD38 | HB-7 | PG |
Brilliant Violet 605™ anti-human CD38 | HB-7 | FC |
TotalSeq™-C0410 anti-human CD38 | HB-7 | PG |
APC/Fire™ 810 anti-human CD38 | HB-7 | FC |
TotalSeq™-D0410 anti-human CD38 | HB-7 | PG |
Customers Also Purchased
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
-
Purified anti-human CD38
Human peripheral blood lymphocytes were stained with purifie... -
PE anti-human CD38
Human peripheral blood lymphocytes were stained with CD38 (c... -
APC anti-human CD38
Human peripheral blood lympocytes were stained with CD38 (cl... -
PE/Cyanine7 anti-human CD38
Human peripheral blood lymphocytes were stained with CD38 (c... -
FITC anti-human CD38
Human peripheral blood lymphocytes were stained with CD38 (c... -
Brilliant Violet 510™ anti-human CD38
Human peripheral blood lymphocytes were stained with CD38 (c... -
PerCP/Cyanine5.5 anti-human CD38
Human peripheral blood lymphocytes were stained with CD38 (c... -
APC/Cyanine7 anti-human CD38
Human peripheral blood lymphocytes were stained with CD38 (c... -
Brilliant Violet 421™ anti-human CD38
Human peripheral blood lymphocytes were stained with CD38 (c... -
Brilliant Violet 650™ anti-human CD38
Human peripheral blood lymphocytes were stained with CD38 (c... -
PerCP anti-human CD38
Human peripheral blood lymphocytes were stained with CD38 (c... -
Alexa Fluor® 700 anti-human CD38
Human peripheral blood lymphocytes were stained with CD38 (c... -
APC/Fire™ 750 anti-human CD38
Human peripheral blood lymphocytes were stained with CD38 (c... -
Pacific Blue™ anti-human CD38
Human peripheral blood lymphocytes were stained with CD38 (c... -
PE/Dazzle™ 594 anti-human CD38
Human peripheral blood lymphocytes were stained with CD38 (c... -
Alexa Fluor® 647 anti-human CD38
Human peripheral blood lymphocytes were stained with CD38 (c... -
Alexa Fluor® 488 anti-human CD38
Human peripheral blood lymphocytes were stained with CD38 (c... -
TotalSeq™-A0410 anti-human CD38
-
TotalSeq™-B0410 anti-human CD38
-
Brilliant Violet 605™ anti-human CD38
Human peripheral blood lymphocytes were stained with CD3 APC... -
TotalSeq™-C0410 anti-human CD38
-
APC/Fire™ 810 anti-human CD38
Human peripheral blood lymphocytes were stained with CD38 (c... -
TotalSeq™-D0410 anti-human CD38
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