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Alexa Fluor® 488 anti-human PSMA (FOLH1) Antibody

Pricing & Availability
Clone
LNI-17 (See other available formats)
Regulatory Status
RUO
Other Names
PSM, Folate hydrolase 1 (FOLH1), Glutamate carboxypeptidase 2 (GCP2), NAALADase I, FGCP
Isotype
Mouse IgG1, κ
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Product Citations
publications
LNI-17_A488_050609.jpg
Human prostatic adenocarcinoma cell line LNCaP stained with LNI-17 Alexa Fluor® 488
  • LNI-17_A488_050609.jpg
    Human prostatic adenocarcinoma cell line LNCaP stained with LNI-17 Alexa Fluor® 488
Compare all formats See Alexa Fluor® 488 spectral data
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342505 25 tests £101
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342506 100 tests £213
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Description

PSMA (prostate-specific membrane antigen) is a type II transmembrane zinc metallopeptidase, belonging to the M28 peptidase family. It possesses hydrolyzing enzyme activities and is also known as FOLH1 (folate hydrolase 1), GCP2 (glutamate carboxypeptidase II), and NAALADase I (N-acetylated-alpha-linked acidic dipeptidase I). PSMA is expressed by normal and malignant prostate epithelial cells, by urothelial adenocarcinoma, and vasculatures of other malignancies. It is also found in the nervous system.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 488 under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

* Alexa Fluor® 488 has a maximum emission of 519 nm when it is excited at 488 nm.


Alexa Fluor® and Pacific Blue™ are trademarks of Life Technologies Corporation.

View full statement regarding label licenses
Excitation Laser
Blue Laser (488 nm)
Product Citations
  1. Ladurner M, et al. 2021. Biomedicines. 9:. PubMed
  2. Sánchez-Crespo A, et al. 2018. EJNMMI Res. 8:27. PubMed
  3. Knowles S, et al. 2014. Clin Cancer Res. 20:6367. PubMed
  4. Boya M, et al. 2022. Nat Commun. 13:3385. PubMed
RRID
AB_2106439 (BioLegend Cat. No. 342505)
AB_2106439 (BioLegend Cat. No. 342506)

Antigen Details

Structure
Type II transmembrane zinc metallopeptidase, M28 peptidase family
Distribution

Epithelial cells in prostate, intestine and kidney tissue, nervous system

Function
Hydrolyzing enzyme activity
Cell Type
Epithelial cells
Biology Area
Cell Biology
Antigen References

1. Silver DA, et al. 1997. Clin. Cancer Res. 3:81.
2. Troyer JK, et al. 1995. Int. J. Cancer. 62:552.
3. Mannweiler S, et al. 2009. Pathol. Oncol. Res. 15:167.

Gene ID
2346 View all products for this Gene ID
UniProt
View information about PSMA on UniProt.org
Go To Top Version: 2    Revision Date: 06/27/2014

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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