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Alexa Fluor® 647 anti-human MUC-17 Antibody

Pricing & Availability
Clone
MQ155 (See other available formats)
Regulatory Status
RUO
Other Names
Mucin-17, MUC3, MUC-3
Isotype
Mouse IgG1, κ
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Product Citations
publications
MQ155_A647_MUC17_Antibody_041422
Human pancreatic cancer cell line (AsPC-1) was stained with anti-human MUC-17 (clone MQ155) Alexa Fluor® 647 (filled histogram) or mouse IgG1, κ Alexa Fluor® 647 isotype control.
  • MQ155_A647_MUC17_Antibody_041422
    Human pancreatic cancer cell line (AsPC-1) was stained with anti-human MUC-17 (clone MQ155) Alexa Fluor® 647 (filled histogram) or mouse IgG1, κ Alexa Fluor® 647 isotype control.
Compare all formats See Alexa Fluor® 647 spectral data
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395309 25 tests £129
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395310 100 tests £265
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Description

It is a 451 KD glycocylated member of the mucin family with 2 EGF like domains on the C-terminus and serine/tyrosine phosphorylation sites on the cytoplasmic domain. It is expressed by epithelial cells and plays a role in cytoprotection, signal transduction. Expression of this molecule can also render tumor cells to become less adhesive. It interacts with PKDZ1 and increased expression of this molecule has been reported in colon cancer.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Purified recombinant Muc17 protein, Freund’s Complete Adjuvant
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

 

* Alexa Fluor® 647 has a maximum emission of 668 nm when it is excited at 633 nm / 635 nm.


Alexa Fluor® and Pacific Blue™ are trademarks of Life Technologies Corporation.

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Excitation Laser
Red Laser (633 nm)
RRID
AB_2927814 (BioLegend Cat. No. 395309)
AB_2927814 (BioLegend Cat. No. 395310)

Antigen Details

Structure
451 KD N-glycosylate single pass membrane protein
Distribution

Gastrointestinal tract

Function
Cytoprotection, extravasation, signal transduction
Interaction
PDZK1
Biology Area
Cancer Biomarkers, Cell Biology, Cell Motility/Cytoskeleton/Structure, Immunology, Innate Immunity
Antigen References
  1. Malmberg EK, et al. 2008. Biochem J. 410:283.
  2. Gum JR Jr, et al. 2002. Biochem Biophys Res Commun. 291:466.
  3. Hirono S, et al. 2010. Cancer Sci. 101:259.
Gene ID
140453 View all products for this Gene ID
UniProt
View information about MUC-17 on UniProt.org
Go To Top Version: 1    Revision Date: 04/14/2022

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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