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Anti-MRP1 (ABCC1) Antibody (Previously Covance catalog# SIG-38760)

Pricing & Availability
Clone
MRPr1 (See other available formats)
Regulatory Status
RUO
Other Names
ABC29, ABCC, GS-X, MRP, Multidrug resistance-associated protein 1, LTC4 transporter, leukotriene C(4) transporter
Previously
Covance Catalog# SIG-38760
Isotype
Rat IgG2a
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Product Citations
publications
MRPr1_MRP1_ABCC1_Antibody_040819_updated.png
IHC staining of anti-MRP1 (ABCC1) antibody (clone MRPr1) on formalin-fixed paraffin-embedded human liver tissue. Following antigen retrieval using Sodium Citrate H.I.E.R., the tissue was incubated with a 1:20 dilution of the primary antibody for 60 minutes at room temperature. After incubation with biotinylated anti-rat antibody, the tissue was labeled with BioLegend's HRP labeling reagent followed by addition of DAB chromogen (Cat. No. 926506) for detection and hematoxylin counterstaining, according to the protocol provided. The image was captured with a 40X objective. Scale bar 50 µm
  • MRPr1_MRP1_ABCC1_Antibody_040819_updated.png
    IHC staining of anti-MRP1 (ABCC1) antibody (clone MRPr1) on formalin-fixed paraffin-embedded human liver tissue. Following antigen retrieval using Sodium Citrate H.I.E.R., the tissue was incubated with a 1:20 dilution of the primary antibody for 60 minutes at room temperature. After incubation with biotinylated anti-rat antibody, the tissue was labeled with BioLegend's HRP labeling reagent followed by addition of DAB chromogen (Cat. No. 926506) for detection and hematoxylin counterstaining, according to the protocol provided. The image was captured with a 40X objective. Scale bar 50 µm
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907201 500 µL £334
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Description

Clone MRPr1 reacts with an internal epitope of the 190 kD Multidrug Resistance-associated Protein (MRP). This antibody does not cross-react with the human MDR1 and MDR3 P-glycoproteins.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
This antibody was developed against a bacterial fusion protein of MRP containing a segment of 168 amino acids in the amino-proximal half of the protein.
Formulation
Tissue Culture Supernatant (in PBS with BSA + 0.09% NaN3).

Previous lots of this product may have been formulated with 0.1% or 0.05% NaN3 instead of 0.09% NaN3. For further information please contact BioLegend Technical Support or Customer Service.
Preparation
Tissue Culture Supernatant
Storage & Handling
Store between 2°C and 8°C.
Application

IHC-P - Quality tested
ICC, ELISA, WB, IHC-F - Reported in the literature, not verified in house
Recommended Usage

Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a dilution range of 1:20 - 1:40 is suggested. It is recommended that the reagent be titrated for optimal performance for each application.

Application References

(PubMed link indicates BioLegend citation)
  1. Scheffer GL, et al.2000. Cancer Res. 60:5269 (ICC, ELISA, WB, IHC-F, IHC-P).
RRID
AB_2565074 (BioLegend Cat. No. 907201)

Other Formats

View All MRP1 Reagents Request Custom Conjugation
Description Clone Applications
Anti-MRP1 (ABCC1) MRPr1 IHC-P,ICC,ELISA,WB,IHC-F
Go To Top Version: 6    Revision Date: 02/08/2024

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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