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APC anti-human CD298 Antibody

Pricing & Availability
Clone
LNH-94 (See other available formats)
Regulatory Status
RUO
Other Names
Na+/K+ ATPase β3, ATP1B3
Isotype
Mouse IgG1, κ
Ave. Rating
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Product Citations
publications
LNH-94_APC_CD298_Antibody_FC_091014.jpg
Human peripheral blood lymphocytes were stained with CD298 (clone LNH-94) APC (filled histogram) or mouse IgG1, κ APC isotype control (open histogram).
  • LNH-94_APC_CD298_Antibody_FC_091014.jpg
    Human peripheral blood lymphocytes were stained with CD298 (clone LNH-94) APC (filled histogram) or mouse IgG1, κ APC isotype control (open histogram).
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341706 100 tests £256
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Description

CD298 or the β3 Na+/K+ ATPase, is a 42 kD type II transmembrane protein, also known as ATP1B3. An integral plasma membrane protein, Na+/K+ ATPase is composed of one α and one β subunits. Four isoforms of the α and three isoforms of the β subunits have been reported. Na+/K+ ATPase couples ATP hydrolysis to the development of an ionic gradient by pumping Na+ and K+ ions in opposite directions across the cell plasma membrane. It has broad tissue distribution, including all leukocytes and many other tissues.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Human
Reported Reactivity
African Green, Baboon, Cynomolgus, Rhesus
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Red Laser (633 nm)
Product Citations
  1. Servetto A, et al. 2021. Clin Cancer Res. 27:4379. PubMed
  2. Kurelac I, et al. 2019. Nat Commun. 10:903. PubMed
  3. Chan T, et al. 2016. J Exp Med. 213(13):2967-2988. PubMed
RRID
AB_2564263 (BioLegend Cat. No. 341706)

Antigen Details

Structure
CD298 is the β3 subunit of Na+/K+ ATPase, type II transmembrane protein
Distribution

Broad expression including all leukocytes and other tissues

Function
sodium-potassium pump, moves these Na+ and K+ ions in opposite directions across cell plasma membrane
Biology Area
Immunology
Molecular Family
CD Molecules
Antigen References

1. Zola H, et al. 2007. Leukocyte and Stromal Cell Molecules:The CD Markers Wiley-Liss A John Wiley & Sons Inc, Publication
2. Chiampanichayakul S, et al. 2006. Tissue Antigens. 68:509
3. Malik N, et al. 1996. J. Biol. Chem. 271:22754

Gene ID
483 View all products for this Gene ID
UniProt
View information about CD298 on UniProt.org
Go To Top Version: 1    Revision Date: 09/17/2014

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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