- Clone
- S19008G (See other available formats)
- Regulatory Status
- RUO
- Other Names
- CLEC4C, CLECSF11, CLECSF7, DLEC, HECL
- Isotype
- Mouse IgG2a, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
314407 | 25 tests | £102 | ||||
314408 | 100 tests | £321 |
CD303, also known as BDCA-2 and CLEC4C, is a 38 kD type II transmembrane glycoprotein. It is a member of the C-type lectin superfamily. CD303 is expressed by plasmacytoid dendritic cells (pDCs) and is involved in cell adhesion, signaling, and antigen capture and processing. Crosslinking of CD303 inhibits the production of IFN-α/β and TLR-9 induced pDCs maturation.
Product Details
Product Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Human CLEC4C-transfectants
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
-
Red Laser (633 nm)
- RRID
-
AB_2910386 (BioLegend Cat. No. 314407)
AB_2910386 (BioLegend Cat. No. 314408)
Antigen Details
- Structure
- Type II transmembrane protein, 38 kD, member of the C-type lectin superfamily
- Distribution
-
Plasmacytoid dendritic cells
- Function
- Antigen capture, inhibition of IFN α/β production
- Cell Type
- Dendritic cells
- Biology Area
- Costimulatory Molecules, Immunology, Innate Immunity
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. Jähn PS, et al. 2010. Cell. Immunol. 265:15.
2. Graham LM and Brown GD. 2009. Cytokine. 48:148. - Gene ID
- 170482 View all products for this Gene ID
- UniProt
- View information about CD303 on UniProt.org
Related FAQs
Other Formats
View All CD303 Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-human CD303 (BDCA-2) Antibody | S19008G | FC |
PE anti-human CD303 (BDCA-2) Antibody | S19008G | FC |
APC anti-human CD303 (BDCA-2) Antibody | S19008G | FC |
FITC anti-human CD303 (BDCA-2) | S19008G | FC |
PE/Fire™ 810 anti-human CD303 (BDCA-2) | S19008G | FC |
APC anti-human CD303 | S19008G | FC |
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Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-human CD303 (BDCA-2) Antibody
Human peripheral mononuclear cells were stained with anti-hu... -
PE anti-human CD303 (BDCA-2) Antibody
Human peripheral mononuclear cells were stained with anti-hu... -
APC anti-human CD303 (BDCA-2) Antibody
Human peripheral mononuclear cells were treated with Human T... -
FITC anti-human CD303 (BDCA-2)
Human peripheral mononuclear cells were treated with Human T... -
PE/Fire™ 810 anti-human CD303 (BDCA-2)
Human peripheral mononuclear cells were treated with Human T... -
APC anti-human CD303
Typical results from human peripheral blood mononuclear cell...
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