- Clone
- QA20A59 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Adhesion G protein-coupled receptor E3; EGF module-containing mucin-like hormone receptor 3
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
![QA20A59_APC_EMR3_Antibody_120822 QA20A59_APC_EMR3_Antibody_120822](https://d1spbj2x7qk4bg.cloudfront.net/Admin/Public/GetImage.ashx?Image=/Files/Images/media_assets/products/product_images/QA20A59_APC_EMR3_Antibody_120822-.png&Width=240&Height=300&altFmImage_path=&Compression=90&Crop=5)
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Human peripheral blood granulocytes were stained with anti-human EMR3 recombinant (clone QA20A59) APC (filled histogram) or mouse IgG1, κ APC isotype control (open histogram).
Cat # | Size | Price | Quantity Check Availability | Save | ||
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366105 | 25 tests | £113 | ||||
366106 | 100 tests | £249 |
EMR3 is a member of the EGF-7 transmembrane (TM7) adhesion GPCR family. It is predominantly expressed on granulocytes, neutrophils, monocytes, and macrophages, and at lower levels on mature myeloid cells and dendritic cells. EMR3 is absent on lymphocytes, hematopoietic stem cells and myeloid progenitors.
Studies suggest that the EMR3 molecule is upregulated during late stages of neutrophil differentiation and is a marker for terminally differentiated cells. EMR3 may play a role in myeloid-myeloid interactions during immune and inflammatory responses.
Product Details
- Verified Reactivity
- Human
- Antibody Type
- Recombinant
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
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FC - Quality tested
- Recommended Usage
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Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
-
Red Laser (633 nm)
- RRID
-
AB_2928026 (BioLegend Cat. No. 366105)
AB_2928026 (BioLegend Cat. No. 366106)
Antigen Details
- Structure
- EGF-like domain, 7-transmembrane
- Distribution
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Granulocytes, neutrophils, monocytes, macrophages, dendritic cells
- Function
- Adhesion, myeloid-myeloid cell interaction
- Cell Type
- Dendritic cells, Granulocytes, Monocytes, Neutrophils
- Biology Area
- Adaptive Immunity, Cell Adhesion, Immunology, Innate Immunity
- Molecular Family
- Adhesion Molecules, GPCR
- Antigen References
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- Matmati M. et al. 2007, J Leukoc Biol. 81:440-8.
- Stacey M, et al. 2001. J Biol Chem. 276:18863-70.
- Gene ID
- 84658 View all products for this Gene ID
- UniProt
- View information about EMR3 on UniProt.org
Related FAQs
Other Formats
View All EMR3 Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-human EMR3 Recombinant Antibody | QA20A59 | FC |
PE anti-human EMR3 Recombinant Antibody | QA20A59 | FC |
APC anti-human EMR3 Recombinant Antibody | QA20A59 | FC |
FITC anti-human EMR3 Recombinant Antibody | QA20A59 | FC |
PE/Cyanine7 anti-human EMR3 Recombinant Antibody | QA20A59 | FC |
PerCP/Cyanine5.5 anti-human EMR3 Recombinant Antibody | QA20A59 | FC |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-human EMR3 Recombinant Antibody
Human peripheral blood granulocytes were stained with purifi... -
PE anti-human EMR3 Recombinant Antibody
Human peripheral blood granulocytes were stained with anti-h... -
APC anti-human EMR3 Recombinant Antibody
Human peripheral blood granulocytes were stained with anti-h... -
FITC anti-human EMR3 Recombinant Antibody
Human peripheral blood granulocytes were stained with anti-h... -
PE/Cyanine7 anti-human EMR3 Recombinant Antibody
Human peripheral blood granulocytes were stained with anti-h... -
PerCP/Cyanine5.5 anti-human EMR3 Recombinant Antibody
Human peripheral blood granulocytes were stained with anti-h...
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