- Clone
- OX-97 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Lyb-8, BL-CAM
- Isotype
- Rat IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
126109 | 25 µg | £86 | ||||
126110 | 100 µg | £183 |
CD22 is a member of the sialoadhesion family.CD22 is expressed on the surface of a subpopulation of mature B lymphocytes and may modulate signaling through the B cell antigen receptor. The OX-97 monoclonal antibody recognizes the second domain of the CD22.
Product DetailsProduct Details
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
-
Red Laser (633 nm)
- Product Citations
-
- RRID
-
AB_2561629 (BioLegend Cat. No. 126109)
AB_2561629 (BioLegend Cat. No. 126110)
Antigen Details
- Structure
- 130-150 kd type 1 transmembrane glycoprotein. It is a member of the Siglec family and Ig superfamily.
- Distribution
-
CD22 is expressed in the cytoplasm of pro-B and pre-B cells, and on the surface of mature B and activated B cells, but not on plasma cells.
- Function
- B cell signaling and adhesion.
- Interaction
- Associates with SHP-1, Syk, Lck, Lyn and others.
- Cell Type
- B cells
- Biology Area
- Immunology
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. Symington FW et al. 1982. Immunogenetics 16:381
2. Erickson LD et al. 1996. Int Immunol 8:1121
3. Doody GM et al. 1995. Science 269:242 - Gene ID
- 12483 View all products for this Gene ID
- UniProt
- View information about CD22 on UniProt.org
Other Formats
View All CD22 Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
FITC anti-mouse CD22 | OX-97 | FC |
Alexa Fluor® 647 anti-mouse CD22 | OX-97 | FC,IHC-F,3D IHC |
APC anti-mouse CD22 | OX-97 | FC |
PE anti-mouse CD22 | OX-97 | FC |
TotalSeq™-A0827 anti-mouse CD22 | OX-97 | PG |
TotalSeq™-C0827 anti-mouse CD22 | OX-97 | PG |
TotalSeq™-B0827 anti-mouse CD22 | OX-97 | PG |
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Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
-
FITC anti-mouse CD22
C57BL/6 splenocytes stained with OX-97 FITC -
Alexa Fluor® 647 anti-mouse CD22
C57BL/6 splenocytes stained with OX-97 Alexa Fluor® 647 C57BL/6 mouse frozen spleen section was fixed with 4% parafo... Paraformaldehyde-fixed (4%), 500 μm-thick mouse spleen secti... -
APC anti-mouse CD22
C57BL/6 mouse splenocytes were stained with CD22 (clone OX-9... -
PE anti-mouse CD22
C57BL/6 mouse splenocytes were stained with CD22 (clone OX-9... -
TotalSeq™-A0827 anti-mouse CD22
-
TotalSeq™-C0827 anti-mouse CD22
-
TotalSeq™-B0827 anti-mouse CD22
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