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APC anti-mouse CD36 Antibody

Pricing & Availability
Clone
HM36 (See other available formats)
Regulatory Status
RUO
Other Names
FAT, gpIIIb, gpIV
Isotype
Armenian Hamster IgG
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Product Citations
publications
HM36_APC_022607
Thioglycollate-elicited BALB/c mouse peritoneal macrophages stained with HM36 APC
  • HM36_APC_022607
    Thioglycollate-elicited BALB/c mouse peritoneal macrophages stained with HM36 APC
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102611 25 µg £70
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102612 100 µg £215
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Description

CD36 is a 85 kD glycoprotein, also known as FAT, gpIIIb, or gpIV. It is a member of the class B scavenger receptor family, expressed on platelets, monocytes, macrophages, megakaryocytes, microvasculature, dendritic cells and mammary endothelial cells. The primary ligands for CD36 have been reported to be oxidized low density lipoprotein, anionic phospholipids, and collagens I, IV, and V. CD36 acts as a scavenger receptor thus promoting the removal of apoptotic neutrophils and other apoptotic bodies, as well as clearance of defective erythrocytes.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Armenian Hamster
Immunogen
Full length version of the protein
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Excitation Laser
Red Laser (633 nm)
Application References

(PubMed link indicates BioLegend citation)
  1. Hamilton R F, 2006. J. Biol. Chem. 281:34218.
  2. Stuart L M, 2007. J. Biol. Chem. doi:10.1074/jbc.M702887200.
  3. Hu Q, 2018. Nat Biomed Eng. 2(11): 831.
Product Citations
  1. Hickman S, et al. 2008. J Neurosci. 28:8354. PubMed
  2. Yuan O, et al. 2022. Sci Adv. 8:eabm9987. PubMed
  3. Kim D, et al. 2021. Nanomicro Lett. 13:31. PubMed
  4. De Silva N, et al. 2016. Proc Natl Acad Sci U S A. 113: 9063 - 9068. PubMed
  5. Misumi I et al. 2019. Cell Rep. 27(2):514-524 . PubMed
  6. Ma X, et al. 2021. Cell Metabolism. 33(5):1001-1012.e5. PubMed
  7. Choi Y, et al. 2021. Cell Mol Gastroenterol Hepatol. 12:1761. PubMed
  8. Miska J et al. 2019. Cell reports. 27(1):226-237 . PubMed
  9. Macdougall CE et al. 2018. Cell metabolism. 27(3):588-601 . PubMed
  10. Choi SH, et al. 2020. Arterioscler Thromb Vasc Biol. :ATVBAHA120315485. PubMed
  11. Singhal P, et al. 2016. Proc Natl Acad Sci U S A. 113: 122 - 127. PubMed
  12. de Haan W, et al. 2020. Am J Physiol Gastrointest Liver Physiol. G803:318. PubMed
  13. Chakraborty P, et al. 2020. Cell Reports. 28(7):1879-1893.e7.. PubMed
  14. Kitaura A, et al. 2021. PLoS One. 16:e0245957. PubMed
RRID
AB_571994 (BioLegend Cat. No. 102611)
AB_571994 (BioLegend Cat. No. 102612)

Antigen Details

Structure
Scavenger receptor superfamily, 85 kD
Distribution

Platelets, monocytes, macrophages, microvascular and mammary endothelial cells

Function
Scavenger receptor, recognition and phagocytosis of apoptotic neutrophils, adhesion
Ligand/Receptor
Oxidized low density lipoprotein, anionic phospholipids, collagen I, IV, and V
Cell Type
Endothelial cells, Macrophages, Monocytes, Platelets
Biology Area
Immunology, Innate Immunity
Molecular Family
CD Molecules
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Greenwalt DE, et al. 1992. Blood 80:1105.
3. Endemann G, et al. 1993. J. Biol. Chem. 268:11811.

Gene ID
12491 View all products for this Gene ID
UniProt
View information about CD36 on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 1    Revision Date: 11/30/2012

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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