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Biotin anti-human CD93 Antibody

Pricing & Availability
Clone
VIMD2 (See other available formats)
Regulatory Status
RUO
Workshop
VI MR8
Other Names
GR11, C1qRp, C1qR1, CDw93
Isotype
Mouse IgG1, κ
Ave. Rating
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Product Citations
publications
VIMD2_Biotin_100908.jpg
Human peripheral blood monocytes stained with biotinylated VIMD2, followed by Sav-PE
  • VIMD2_Biotin_100908.jpg
    Human peripheral blood monocytes stained with biotinylated VIMD2, followed by Sav-PE
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336104 100 µg £177
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Description

CD93 is a 110 kD O-sialoglycoprotein, known as complement C1q receptor, C1qR1, C1qRp (C1q receptor precursor), or GR11. It is expression on monocytes, granulocytes, platelets, and endothelial cells. CD93 regulates phagocytosis of apoptosis cells, and leukocyte-endothelial cell adhesion.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Human
Reported Reactivity
African Green, Baboon, Cynomolgus, Rhesus
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 106 cells in 100 µl volume or 100 µl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Application References

(PubMed link indicates BioLegend citation)
  1. Steinberger P, et al. 2002. J. Leukoc. Biol. 71:133
Product Citations
  1. Antonyshyn JA, et al. 2021. Commun Biol. 4:1205. PubMed
RRID
AB_2076050 (BioLegend Cat. No. 336104)

Antigen Details

Structure
110 kD glycoprotein
Distribution

Monocytes/macrophages, granulocytes, platelets, endothelial cells

Function
C1q receptor, predicted to assist phagocytosis
Ligand/Receptor
Complement C1q
Cell Type
Endothelial cells, Granulocytes, Macrophages, Monocytes, Platelets
Biology Area
Cell Biology, Immunology, Neuroinflammation, Neuroscience
Molecular Family
CD Molecules
Antigen References

1. Zola H et al. ed. 2007. Leukocyte and Stromal Cell Molecules:The CD Markers. A John Wiley & Sons Inc, Publication
2. Nepomuceno RR, et al. 1998. J. Immunol. 160:1929

Gene ID
22918 View all products for this Gene ID
UniProt
View information about CD93 on UniProt.org

Related FAQs

How many biotin molecules are per antibody structure?
We don't routinely measure the number of biotins with our antibody products but the number of biotin molecules range from 3-6 molecules per antibody.
Go To Top Version: 2    Revision Date: 09/01/2022

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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