- Clone
- SA051D1 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- CXCR6, Chemokine (C-X-C motif) receptor 6, BONZO, STRL33, chemokine receptor 6, CD 186, CXC-R6, CXCR-6, C-X-C chemokine receptor type 6
- Isotype
- Rat IgG2b, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
![SA051D1_BV421_CD186_Antibody_1_041416 SA051D1_BV421_CD186_Antibody_1_041416](https://d1spbj2x7qk4bg.cloudfront.net/Admin/Public/GetImage.ashx?Image=/Files/Images/media_assets/products/product_images/SA051D1_BV421_CD186_Antibody_1_041416.jpg&Width=240&Height=300&altFmImage_path=&Compression=90&Crop=5)
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C57BL/6 mouse splenocytes were stained with CD3 PE and CD186 (clone SA051D1) Brilliant Violet 421™ (top) or rat IgG2b, κ Brilliant Violet 421™ isotype control (bottom). -
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
151109 | 50 µg | £200 |
CD186, or CXCR6, is a 39 kD G-protein coupled chemokine receptor with seven transmembrane-spanning regions. Its ligand is CXCL16. It is expressed on different T cell subsets and is upregulated in activated T cells. Expression of CXCR6 is correlated with increased inflammatory responses and seems to contribute to liver fibrosis.
Product DetailsProduct Details
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- mCXCR6-transfectants
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA).
- Preparation
- The antibody was purified by affinity chromatography and conjugated with Brilliant Violet 421™ under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Brilliant Violet 421™ excites at 405 nm and emits at 421 nm. The standard bandpass filter 450/50 nm is recommended for detection. Brilliant Violet 421™ is a trademark of Sirigen Group Ltd.
Learn more about Brilliant Violet™.
This product is subject to proprietary rights of Sirigen Inc. and is made and sold under license from Sirigen Inc. The purchase of this product conveys to the buyer a non-transferable right to use the purchased product for research purposes only. This product may not be resold or incorporated in any manner into another product for resale. Any use for therapeutics or diagnostics is strictly prohibited. This product is covered by U.S. Patent(s), pending patent applications and foreign equivalents. - Excitation Laser
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Violet Laser (405 nm)
- Product Citations
-
- RRID
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AB_2616760 (BioLegend Cat. No. 151109)
Antigen Details
- Structure
- G-protein coupled receptor 1 family.
- Distribution
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T cells and natural killer T (NKT) cells.
- Function
- Chemotaxis and the development of T cells.
- Ligand/Receptor
- CXCL16.
- Cell Type
- NKT cells, T cells
- Biology Area
- Cell Biology, Cell Motility/Cytoskeleton/Structure, Immunology, Neuroinflammation, Neuroscience
- Molecular Family
- CD Molecules, Cytokine/Chemokine Receptors, GPCR
- Antigen References
-
1. Kim CH, et al. 2001. J. Clin. Invest. 107:595.
2. Heesch K, et al. 2014. PLoS One. 9:5.
3. Wehr A, et al. 2013. J. Immunol. 190:5226. - Gene ID
- 80901 View all products for this Gene ID
- UniProt
- View information about CD186 on UniProt.org
Related FAQs
- What is the F/P ratio range of our BV421™ format antibody reagents?
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It is lot-specific. On average it ranges between 2-4.
Other Formats
View All CD186 (CXCR6) Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
FITC anti-mouse CD186 (CXCR6) | SA051D1 | FC |
Purified anti-mouse CD186 (CXCR6) | SA051D1 | FC |
PE anti-mouse CD186 (CXCR6) | SA051D1 | FC |
APC anti-mouse CD186 (CXCR6) | SA051D1 | FC |
Brilliant Violet 421™ anti-mouse CD186 (CXCR6) | SA051D1 | FC |
Brilliant Violet 711™ anti-mouse CD186 (CXCR6) | SA051D1 | FC |
PE/Dazzle™ 594 anti-mouse CD186 (CXCR6) | SA051D1 | FC |
PE/Cyanine7 anti-mouse CD186 (CXCR6) | SA051D1 | FC |
Biotin anti-mouse CD186 (CXCR6) | SA051D1 | FC |
Alexa Fluor® 647 anti-mouse CD186 (CXCR6) | SA051D1 | FC |
PerCP/Cyanine5.5 anti-mouse CD186 (CXCR6) Antibody | SA051D1 | FC |
APC/Cyanine7 anti-mouse CD186 (CXCR6) Antibody | SA051D1 | FC |
TotalSeq™-A0926 anti-mouse CD186 (CXCR6) | SA051D1 | PG |
TotalSeq™-C0926 anti-mouse CD186 (CXCR6) | SA051D1 | PG |
APC/Fire™ 750 anti-mouse CD186 (CXCR6) | SA051D1 | FC |
TotalSeq™-B0926 anti-mouse CD186 (CXCR6) | SA051D1 | PG |
Spark Red™ 718 anti-mouse CD186 (CXCR6) (Flexi-Fluor™) | SA051D1 | FC |
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Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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FITC anti-mouse CD186 (CXCR6)
C57BL/6 mouse splenocytes were stained with CD3 PE and CD186... -
Purified anti-mouse CD186 (CXCR6)
C57BL/6 mouse splenocytes were stained with CD3 APC and puri... -
PE anti-mouse CD186 (CXCR6)
C57BL/6 mouse splenocytes were stained with CD3 APC and CD18... -
APC anti-mouse CD186 (CXCR6)
C57BL/6 mouse splenocytes were stained with CD3 PE and CD186... -
Brilliant Violet 421™ anti-mouse CD186 (CXCR6)
C57BL/6 mouse splenocytes were stained with CD3 PE and CD186... -
Brilliant Violet 711™ anti-mouse CD186 (CXCR6)
C57BL/6 mouse splenocytes were stained with CD3e APC and CD1... -
PE/Dazzle™ 594 anti-mouse CD186 (CXCR6)
C57BL/6 mouse splenocytes were stained with CD3e APC and CD1... -
PE/Cyanine7 anti-mouse CD186 (CXCR6)
C57BL/6 mouse splenocytes were stained with CD3ε APC... -
Biotin anti-mouse CD186 (CXCR6)
C57BL/6 mouse splenocytes were stained with CD3 APC and CD18... -
Alexa Fluor® 647 anti-mouse CD186 (CXCR6)
C57BL/6 mouse splenocytes were stained with CD3 PE and CD186... -
PerCP/Cyanine5.5 anti-mouse CD186 (CXCR6) Antibody
C57BL/6 mouse splenocytes were stained with CD3ε FITC and an... -
APC/Cyanine7 anti-mouse CD186 (CXCR6) Antibody
C57BL/6 mouse splenocytes were stained with CD3ε FITC and an... -
TotalSeq™-A0926 anti-mouse CD186 (CXCR6)
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TotalSeq™-C0926 anti-mouse CD186 (CXCR6)
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APC/Fire™ 750 anti-mouse CD186 (CXCR6)
C57BL/6 mouse splenocytes were stained with anti-mouse CD3e ... -
TotalSeq™-B0926 anti-mouse CD186 (CXCR6)
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Spark Red™ 718 anti-mouse CD186 (CXCR6) (Flexi-Fluor™)
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