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- Clone
- DY12 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- P220/240, DY12, DY35
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
-
Human peripheral blood granulocytes stained with DY12 PE
| Cat # | Size | Price | Quantity Check Availability | Save | ||
|---|---|---|---|---|---|---|
| 334403 | 25 tests | £100 | ||||
CD245 is a 220-250 kD transmembrane glycoprotein, also known as p220/240, DY12 or DY35. It is expressed on peripheral blood lymphocytes, monocytes, granulocytes, and platelets. The expression level of CD245 on lymphocytes can be upregulated after 3-7 days stimulation with PHA. It has been reported that CD245 is involved in signal transduction and costimulation of T and NK cells.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Reported Reactivity
- African Green, Baboon, Cynomolgus
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
- Excitation Laser
-
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- RRID
-
AB_1186064 (BioLegend Cat. No. 334403)
Antigen Details
- Distribution
-
Blood lymphocytes, monocytes and granulocytes
- Function
- Signal transduction and costimulation
- Cell Type
- Granulocytes, Lymphocytes, Monocytes
- Biology Area
- Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
1. H. Zola et al. Eds. 2007. Leukocyte and Stromal Cell Molecule:The CD Markers. WILEY-LISS:A John Wiley & Sons Inc, Publication
- Gene ID
- 4863 View all products for this Gene ID
- UniProt
- View information about CD245 on UniProt.org
Related FAQs
- What type of PE do you use in your conjugates?
- We use R-PE in our conjugates.
Other Formats
View All CD245 Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| Purified anti-human CD245 (p220/240) | DY12 | FC |
| PE anti-human CD245 (p220/240) | DY12 | FC |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-human CD245 (p220/240)
Human peripheral blood lymphocytes stained with purified DY1... -
PE anti-human CD245 (p220/240)
Human peripheral blood granulocytes stained with DY12 PE
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