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PE anti-human CD56 (Subset MSC Marker) Antibody

Pricing & Availability
Clone
39D5 (See other available formats)
Regulatory Status
RUO
Workshop
V NK57
Other Names
NCAM-1
Isotype
Mouse IgG1, κ
Ave. Rating
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Product Citations
publications
39D5_PE_CD56_Antibody_011322
Human retinoblastoma cell line WERI-RB-1 stained with anti-human CD56 (Subset MSC Marker) (clone 39D5) PE (filled histogram) or mouse IgG1, κ PE isotype control (open histogram).
  • 39D5_PE_CD56_Antibody_011322
    Human retinoblastoma cell line WERI-RB-1 stained with anti-human CD56 (Subset MSC Marker) (clone 39D5) PE (filled histogram) or mouse IgG1, κ PE isotype control (open histogram).
See PE spectral data
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355503 25 tests £92
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355504 100 tests £230
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Description

CD56 is a single transmemberane glycoprotein also known as NCAM (neural cell adhesion molecule). It is a member of the Ig superfamily. The 140 kD isoform is expressed on NK cells and NK-T cells. CD56 is also expressed in the brain (cerebellum and cortex) and at neuromuscular junctions. Certain large granular lymphocyte (LGL) leukemias, small-cell lung carcinomas, neuronal derived tumors, myelomas, and myeloid leukemias also express CD56. CD56 plays a role in homophilic and heterophilic adhesion via binding to itself or heparin sulfate.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
KG1a cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Clone 39D5 recognizes the epitope of CD56 that is selectively expressed on a subset of mesenchymal stem cells (MSC) population which are CD271bright cells.  It does not efficiently recognize natural killer cells. 

Product Citations
  1. Peck BD, et al. 2022. FASEB J. 36:e22155. PubMed
  2. Toriyama M, et al. 2023. Front Mol Biosci. 10:1149828. PubMed
  3. de Andrade LF, et al. 2019. JCI Insight. 4:e133103. PubMed
  4. Guo M, et al. 2021. Front Oncol. 11:632540. PubMed
  5. Motedayyen H, et al. 2017. BMC Res Notes. . 10.1186/s13104-017-2880-6. PubMed
RRID
AB_2561552 (BioLegend Cat. No. 355503)
AB_2561552 (BioLegend Cat. No. 355504)

Antigen Details

Distribution

Mesenchymal stem cells

Cell Type
Mesenchymal Stem Cells
Biology Area
Cell Biology, Costimulatory Molecules, Immunology, Neuroscience, Stem Cells, Synaptic Biology
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Battula VL, et al. 2009. Haematologica 94:173.

Gene ID
4684 View all products for this Gene ID
UniProt
View information about CD56 on UniProt.org

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 1    Revision Date: 11/30/2012

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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