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- Clone
- L205G1 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- DADR, DRD1A, DRD1
- Isotype
- Mouse IgG2b, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
-
Human DRD1-transfected cells were stained with anti-DRD1 (clone L205G1) PE (filled histogram) or mouse IgG2b, κ PE isotype control (open histogram).
| Cat # | Size | Price | Quantity Check Availability | Save | ||
|---|---|---|---|---|---|---|
| 366403 | 25 tests | £105 | ||||
| 366404 | 100 tests | £247 | ||||
Dopamine receptors are a family of G protein-coupled receptors, which is composed of at least five (D1-D5) members. The D1 subtype is the most common receptor in the central nervous system. It is primarily expressed in caudate putamen in humans. This receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. It plays a role in neuronal growth and development along with behavioral responses. The D1 receptor also modulates D2-mediated events. There are two variants of this gene due to alternate transcription initiation sites.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Human DRD1-transfectants.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
- Excitation Laser
-
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Product Citations
-
- RRID
-
AB_2565469 (BioLegend Cat. No. 366403)
AB_2565469 (BioLegend Cat. No. 366404)
Antigen Details
- Structure
- G protein-coupled receptor.
- Distribution
-
DRD1 Transfected cells.
- Function
- Stimulate adenylyl cyclase and activate cyclic AMP-dependent protein kinases.
- Ligand/Receptor
- Dopamine.
- Cell Type
- Dopaminergic Neurons
- Biology Area
- Cell Biology, Immunology, Neuroscience, Neuroscience Cell Markers, Synaptic Biology
- Molecular Family
- CD Molecules, GPCR, Postsynaptic proteins
- Antigen References
-
1. Fresnoza S, et al. 2014. J. Neurosci. 34(7):2744.
2. Mizuta K, et al. 2013. Respir. Res. 14:89.
3. Zhu F, et al. 2013. PLoS One 8(8):e70805.
4. Levy F, et al. 2013. J. Child Adolesc. Psychopharmacol. 6:423. - Gene ID
- 1812 View all products for this Gene ID
- UniProt
- View information about Dopamine Receptor D1 on UniProt.org
Related FAQs
- What type of PE do you use in your conjugates?
- We use R-PE in our conjugates.
Other Formats
View All Dopamine Receptor D1 Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| PE anti-human Dopamine Receptor D1 | L205G1 | FC |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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PE anti-human Dopamine Receptor D1
Human DRD1-transfected cells were stained with anti-DRD1 (cl...
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