- Clone
- QA20A05 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- GPR5, CCXCR1, mXCR1, Lymphotactin receptor, SCM1 receptor, XC chemokine receptor 1
- Isotype
- Rat IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
109405 | 25 µg | £110 | ||||
109406 | 100 µg | £233 |
XCR1, also known as GPR5 or CCXCR1, is a 38 kD, G-protein coupled, seven transmembrane receptor, and the only member of the "C" chemokine receptor family. XCR1 mediates chemotaxis of XCL1 and XCL2 (lymphotactin-1 and -2), and defines a subset of CD8α+ conventional dendritic cells capable of antigen cross-presentation.
Product DetailsProduct Details
- Verified Reactivity
- Mouse, Rat
- Antibody Type
- Recombinant
- Host Species
- Rat
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- Concentration
- 0.2 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
-
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
-
Clone QA20A05 can completely block the binding of clone ZET on target cells.
- RRID
-
AB_3097312 (BioLegend Cat. No. 109405)
AB_3097312 (BioLegend Cat. No. 109406)
Antigen Details
- Structure
- Only member of the "C" chemokine receptor family, seven transmembrane receptor, coupled to G protein, 38 kD.
- Distribution
-
Subset of CD8α+ conventional dendritic cells.
- Function
- Mediates chemotaxis to XCL1, defines a population of CD8α+ dendritic cells capable of antigen cross-presentation to CD8+ T cells.
- Ligand/Receptor
- XCL1 and XCL2
- Antigen References
-
- Yamazaki C, et al. 2013. J Immunol. 190:6071-82.
- Shimizu K, et al. 2013. J Immunol. 190:5609-19.
- Bachem A, et al. 2012. Front Immunol. 3:214.
- Crozat K, et al. 2011. J Immunol. 187:4411-5.
- Gene ID
- 23832 View all products for this Gene ID 301086 View all products for this Gene ID
- UniProt
- View information about XCR1 on UniProt.org
Related Pages & Pathways
Pages
Related FAQs
- What type of PE do you use in your conjugates?
- We use R-PE in our conjugates.
Other Formats
View All XCR1 Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-mouse/rat XCR1 Recombinant Antibody | QA20A05 | FC |
FITC anti-mouse/rat XCR1 Recombinant Antibody | QA20A05 | FC |
PE anti-mouse/rat XCR1 Recombinant Antibody | QA20A05 | FC |
APC anti-mouse/rat XCR1 Recombinant Antibody | QA20A05 | FC |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
-
Purified anti-mouse/rat XCR1 Recombinant Antibody
Cells from collagenase-digested C57BL/6 mouse spleen were st... -
FITC anti-mouse/rat XCR1 Recombinant Antibody
Cells from collagenase-digested C57BL/6 mouse spleen were st... -
PE anti-mouse/rat XCR1 Recombinant Antibody
Cells from collagenase-digested C57BL/6 mouse spleen were s... -
APC anti-mouse/rat XCR1 Recombinant Antibody
Cells from collagenase-digested C57BL/6 mouse spleen were st...
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