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- Clone
- 17-206.RecM1 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Blood group antigen H (type 1)
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
-
IHC staining of Purified anti-BG-4 Recombinant (clone 17-206.RecM1) on formalin-fixed paraffin-embedded human antrum (stomach) tissue. The tissue was incubated with primary antibody overnight at 4°C. BioLegend’s Ultra Streptavidin HRP Kit (Multi-Species, DAB, Cat. No. 929501) was used for detection followed by hematoxylin counterstaining. The images were captured using a 10X (panel A) and 40X (panel B) objective. Scale bar: 50 µm
| Cat # | Size | Price | Quantity Check Availability | Save | ||
|---|---|---|---|---|---|---|
| 667551 | 25 µg | £124 | ||||
| 667552 | 100 µg | £301 | ||||
BG-4, also known as blood group antigen H (type 1), is a carbohydrate sequence linked to a protein or ceramide. BG-4 is a precursor to the A and B antigens in the ABO system. For individuals with O type blood, the BG-4 antigen remains unmodified. BG-4 formation is catalyzed by the fucosyltransferase 1 enzyme (FUT1). BG-4 is expressed on erythrocytes and epithelial cells, and is thought to play a role in immune response, cell-cell recognition, and in the structural integrity of cells.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Recombinant
- Host Species
- Mouse
- Immunogen
- This antibody was developed against the SW-403 colon cancer cell line. It is specific for Blood group H (type 1).
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
IHC-P - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 1.0 - 10.0 µg/mL is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
-
With this antibody no antigen retrieval is required.
- RRID
-
AB_3662334 (BioLegend Cat. No. 667551)
AB_3662334 (BioLegend Cat. No. 667552)
Antigen Details
- Structure
- BG-4 is a carbohydrate sequence consisting of a chain of β-D-galactose, β-D-N-acetylglucosamine, β-D-galactose, and 2-linked, α-L-fucose
- Distribution
-
Cytoplasmic, cell surface
- Function
- Cell surface antigen, structural
- Cell Type
- Granulocytes, Macrophages, Monocytes, Neutrophils
- Biology Area
- Cell Biology, Immunology, Innate Immunity, Neuroinflammation, Neuroscience
- Molecular Family
- CD Molecules
- Antigen References
-
- Lloyd KO, et al. 1983. Immunogen. 17:537.
- Sakamoto J, et al. 1984. Mol Immunol. 21:1093.
- Anger BR, et al. 1982. Hybridoma. 1:139.
- Gene ID
- NA
- UniProt
- View information about BG-4 on UniProt.org
Related FAQs
Other Formats
View All BG-4 Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| Purified anti-BG-4 Recombinant Antibody | 17-206.RecM1 | IHC-P |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-BG-4 Recombinant Antibody
IHC staining of Purified anti-BG-4 Recombinant (clone 17-206...
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