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Purified anti-BG-8 Antibody (Previously Covance catalog# SIG-3317)

Pricing & Availability
Clone
F3 (See other available formats)
Regulatory Status
RUO
Other Names
Blood Group Related Antigen BG-8
Previously
Signet Catalog# 317-01
Covance Catalog# SIG-3317
Isotype
Mouse IgM
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Product Citations
publications
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912501 1 mL £275
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Description

BG-8 is also known as blood group Lewis Y F3. The Lewis Y (type 2 chain) antigen is found on the Type 2 blood group oligosaccharides of glycolipids and glycoproteins. It has been detected in large bowel tumors and colorectal carcinomas. It may be useful in the classification of human renal and bladder tumors and is being investigated as a diagnostic marker for several forms of cancer.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
This antibody was developed against SK-LU-3 lung cancer cell lines.
Formulation
Phosphate-buffered solution with BSA + 0.09% NaN3.

Previous lots of this product may have been formulated with 0.1% or 0.05% NaN3 instead of 0.09% NaN3. For further information please contact BioLegend Technical Support or Customer Service.
Preparation
The antibody was purified by ammonium sulfate precipitation.
Storage & Handling
Store between 2°C and 8°C.
Application

IHC-P - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunohistochemical staining.

The optimal working dilution should be determined for each specific assay condition.
• IHC: ≥1:40 for Biotin based detection systems such as USA Ultra Streptavidin Detection (Cat. No. 929501).

Tissue Sections: Formalin-fixed, paraffin-embedded tissues.
Pretreatment: Not required
Incubation: 20 minutes at room temperature

Application Notes

This antibody is effective in immunohistochemistry (IHC).

Positive tissue (human): Colon adenocarcinoma

F3 is specific for Lewis Y (Type 2 Chain).

Application References

(PubMed link indicates BioLegend citation)
  1. Yaziji H, et al. 2006. Mod Pathol. 19:514.
  2. Ordonez NG. 2006. Mod Pathol. 19:34.
  3. Ordonez NG. 2006. Mod Pathol. 19:417.
  4. Ordonez NG. 2000. Am J Surg Pathol. 24: 598.
  5. Zhu ZM, et al. 1995. Biol Reprod. 52:903.
  6. Gaffney RA, et al. 1992. J Urol. 148:1341.
  7. Jordon D, et al. 1989. Am J Pathol 135:931.
Product Citations
  1. Moya-Gonzalvez EM, et al. 2022. Microbiol Spectr. 10:e0177522. PubMed
  2. Rimkute I, et al. 2020. J Biol Chem. 295:15974. PubMed
RRID
AB_2565124 (BioLegend Cat. No. 912501)

Related FAQs

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Go To Top Version: 6    Revision Date: 07/31/2024

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

  • Purified anti-BG-8

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