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- Clone
- L403H11 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Eotaxin, eotaxin-1, small inducible cytokine subfamily A, member 11 (SCYA11)
- Isotype
- Rat IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
| Cat # | Size | Price | Quantity Check Availability | Save | ||
|---|---|---|---|---|---|---|
| 683202 | 500 µg | £201 | ||||
CCL11 is a member of the CC chemokine family. It was originally identified as a chemoattractant for eosinophils, and participates in a variety of allergic responses to allergens. CCL11 induces angiogenic responses in CCR3+ microvascular endothelial cells and facilitates the proliferation and metastasis of CCR3+ tumor cells.
Product DetailsProduct Details
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Recombinant Mouse CCL11, (amino acids (His24-Pro97, Accession# NM_011330), were expressed in E. coli.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
ELISA Capture - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by ELISA. For ELISA capture applications, a concentration of 0.5 µg/mL is recommended. To obtain a linear standard curve, serial dilutions of CCL11 recombinant protein ranging from 500 to 7.81 pg/mL are recommended for each ELISA plate. It is recommended that the reagent be titrated for optimal performance.
- RRID
-
AB_2686953 (BioLegend Cat. No. 683202)
Antigen Details
- Structure
- Chemokine
- Distribution
-
Epithelial cells, smooth muscle cells, dendritic cells, fibroblasts, mast cells, and Th2 lymphocytes.
- Function
- Recruits eosinophils in allergic responses. Stimulates eosinophil release from bone marrow, increasing levels of circulating eosinophils. Induced by pro-inflammatory cytokines (IL-4, IL-13, TNF-7alpha;, and IFN-α).
- Interaction
- Eosinophils
- Ligand/Receptor
- CCR3
- Cell Type
- Epithelial cells, Dendritic cells, Fibroblasts, Mast cells, Th2, Eosinophils
- Biology Area
- Angiogenesis, Cell Biology, Immunology, Neuroinflammation, Neuroscience
- Molecular Family
- Cytokines/Chemokines
- Antigen References
-
1. Crump MP, et al. 1998. J. Biol. Chem. 273:22471.
2. Conroy DM, et al. 2001. Respir. Res. 2:150.
3. Salcedo R, et al. 2001. J. Immunol. 166:7571.
4. Hadjicharalambous C, et al. 2004. J. Allergy Clin. Immunol. 113:657.
5. Kaehler J, et al. 2006. J. Investig. Med. 54:446.
6. Levina V, et al. 2009. Clin. Cancer Res. 15:2647. - Gene ID
- 20292 View all products for this Gene ID
- UniProt
- View information about CCL11 on UniProt.org
Related FAQs
Other Formats
View All CCL11 Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| Ultra-LEAF™ Purified anti-CCL11 | L403H11 | Block,ELISA Capture,Neut |
| Purified anti-CCL11 | L403H11 | ELISA Capture |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
-
Ultra-LEAF™ Purified anti-CCL11
Ultra-LEAF™ Purified anti-mouse CCL11 Antibody inhibit... 
Ultra-LEAF™ Purified anti-mouse CCL11 Antibody inhibit... -
Purified anti-CCL11
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