- Clone
- CPTC-FABP5-1 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Fatty acid-binding protein 5 (FABP5), Epidermal-type fatty acid-binding protein (E-FABP), Psoriasis-associated fatty acid-binding protein homolog (PA-FABP)
- Isotype
- Mouse IgG1
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
613951 | 25 µg | £83 | ||||
613952 | 100 µg | £284 |
Fatty Acid Binding Protein 5 (FABP5) is a protein that plays an important role in the regulation of cellular fatty acid metabolism. Initially discovered in epidermal cells, FABP5 binds long-chain fatty acids and other related hydrophobic molecules to facilitate their uptake into the cell. Utilizing this transport function, FABP5 plays an important role in regulating fatty acid metabolism and energy homeostasis. Additionally, FABP5 is capable of transporting lipid-based signaling molecules such as endocannabinoids, functioning in diverse pathways such as glucose homeostasis, retinoic acid signaling, and the inflammatory response.
Product DetailsProduct Details
- Verified Reactivity
- Human, Mouse, Rat
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Recombinant full-length human FABP5
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
IHC-P - Verified - Recommended Usage
-
Each lot of this antibody is quality control tested by western blotting. For western blotting, the suggested use of this reagent is 0.25 - 1.0 µg/mL. For immunohistochemistry on formalin-fixed paraffin-embedded tissue sections, a concentration range of 0.25 - 1.0 µg/mL is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
-
For IHC-P, titration to concentrations below 0.25 µg/mL may improve results.
- RRID
-
AB_2941614 (BioLegend Cat. No. 613951)
AB_2941614 (BioLegend Cat. No. 613952)
Antigen Details
- Structure
- FABP5 is a 135 amino-acid protein with a predicted molecular weight of 15.1 kD.
- Distribution
-
Plasma membrane, keratinocytes and epithelial cells
- Function
- Transporter
- Ligand/Receptor
- Long-chain fatty acids and related lipids
- Cell Type
- Epithelial cells
- Biology Area
- Neuroscience, Signal Transduction
- Molecular Family
- Neurotransmitter Receptor Trafficking/Endocytosis
- Antigen References
-
- Hotamisligil GS and Bernlohr DA. 2015. Nat Rev Endocrinol. 11:592-605.
- Nowowiejska J, et al. 2022. Metabolites. 12:833.
- Xu B, et al. 2022. Front Cell Dev Biol. 10:857919.
- Gene ID
- 2171 View all products for this Gene ID
- UniProt
- View information about FABP5 on UniProt.org
Related Pages & Pathways
Pages
Related FAQs
Other Formats
View All FABP5 Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-FABP5 | CPTC-FABP5-1 | WB,IHC-P |
Compare Data Across All Formats
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Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
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