Purified anti-FMIP Antibody (Previously Covance catalog# MMS-5281)

Pricing & Availability
Clone
F6D/11 (See other available formats)
Regulatory Status
RUO
Other Names
THOC5, C22orf19, PK1.3, fSAP79, hTREX90, THO complex subunit 5 homolog, PP39.2, hTREX90, placental protein 39.2, Fms-interacting protein, NF2/meningioma region protein pK1.3, functional spliceosome-associated protein 79
Previously
Covance Catalog# MMS-5281
Isotype
Mouse IgG1, κ
Ave. Rating
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Product Citations
publications
F6Dslash11_Purified_FMIP_Antibody_WB_021519_updated.png
Western blot of purified anti-FMIP antibody (clone F6D/11). Lane 1: Molecular weight marker; Lane 2: 30 µg of HeLa cell lysate; Lane 3: 30 µg of 3T3 cell lysate; Lane 4: 25 µg of PC12 cell lysate; Lane 5: 30 µg of CHO cell lysate . The blot was incubated with 1 µg/mL of the primary antibody overnight at 4°C, followed by incubation with HRP labeled goat anti-mouse IgG (Cat. No. 405306). Enhanced chemiluminescence was used as the detection system.
  • F6Dslash11_Purified_FMIP_Antibody_WB_021519_updated.png
    Western blot of purified anti-FMIP antibody (clone F6D/11). Lane 1: Molecular weight marker; Lane 2: 30 µg of HeLa cell lysate; Lane 3: 30 µg of 3T3 cell lysate; Lane 4: 25 µg of PC12 cell lysate; Lane 5: 30 µg of CHO cell lysate . The blot was incubated with 1 µg/mL of the primary antibody overnight at 4°C, followed by incubation with HRP labeled goat anti-mouse IgG (Cat. No. 405306). Enhanced chemiluminescence was used as the detection system.
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833401 100 µL £189
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Description

FMIP, also known as FMS-Interacting Protein and THOC5, is a member of the THO complex, which is part of the larger TREX (transcription/export) complex. The TREX complex binds specifically to spliced mRNA, where it binds upstream of the exon-junction complex and aids in mRNA export. TREX machinery is also utilized by Kaposi’s sarcoma-associated herpesvirus and certain other viruses for the propagation of virus production. FMIP may also be involved in granulocyte and adipocyte differentiation.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Human, Mouse, Rat, Hamster
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
This monoclonal antibody was raised against a bacterially expressed C-terminal recombinant GST fusion protein derived from 3' 2.25 kb EcoRV-EcoR1 FMIP cDNA fragment.
Formulation
Phosphate-buffered solution.
Preparation
The antibody was purified by affinity chromatography.
Concentration
1 mg/ml
Storage & Handling
This antibody should be handled aseptically as it is free of preservatives such as Sodium Azide. Store this antibody undiluted between 2°C and 8°C. Please note the storage condition for this antibody has been changed from -20°C to between 2°C and 8°C. You can also check the vial label or CoA to find the proper storage conditions.
Application

WB - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 1 - 10 µg per ml. It is recommended that the reagent be titrated for optimal performance for each application.

RRID
AB_2564966 (BioLegend Cat. No. 833401)

Antigen Details

Structure
Expected MW: 89 kD
Biology Area
Cell Biology, Neuroinflammation, Neuroscience
Gene ID
8563 View all products for this Gene ID
UniProt
View information about FMIP on UniProt.org
Go To Top Version: 4    Revision Date: 07/09/2024

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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