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- Clone
- AC11.AE12 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- HIV TAT
- Previously
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Covance Catalog# MMS-116P
- Isotype
- Mouse IgG1
- Ave. Rating
- Submit a Review
- Product Citations
- publications
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Western blot analysis of recombinant HIV-TAT protein. Lane 1: MW Marker; Lane 2: 50ng of protein; Lane 3: 100ng of protein.
| Cat # | Size | Price | Quantity Check Availability | Save | ||
|---|---|---|---|---|---|---|
| 919001 | 250 µL | £257 | ||||
The HIV-1 TAT (transactivator of transcription) gene codes for a 14 kD protein and is vital for HIV-1 transcription. After infection, TAT is one of the first proteins expressed after HIV has taken over the host’s machinery. TAT is a RNA binding protein that recognizes the TAR (Transactivator Response Element) sequence found in the HIV-1 RNA molecule. It is also needed for the recruitment of the host positive transcription elongation factor b (p-TEFb). In neuron cells, TAT has been linked to progressive neuronal deregulation, HIV-Associated Neurocognitive Disorders and accelerating brain aging.
Product DetailsProduct Details
- Verified Reactivity
- HIV
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- This antibody was generated against full-length HIV TAT protein.
- Formulation
- Phosphate-buffered solution + 0.03% Thimerosal.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 1 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C. Please note the storage condition for this antibody has been changed from -20°C to between 2°C and 8°C. You can also check your vial or your CoA to find the most accurate storage condition for this antibody.
- Application
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WB
- Recommended Usage
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Each lot of this antibody is quality control tested by Western blotting.
The optimal working dilution should be determined for each specific assay condition.
• WB: 1:1,000* - Application Notes
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This antibody is effective in immunoblotting (WB).
*Predicted MW = 11 kD
The epitope is contained in the first 37 amino acids of the protein. - Product Citations
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- RRID
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AB_2565207 (BioLegend Cat. No. 919001)
Antigen Details
- Biology Area
- Bacterial proteins and Toxins, Cell Biology
- Gene ID
- 155871 View all products for this Gene ID
- UniProt
- View information about HIV TAT on UniProt.org
Other Formats
View All HIV TAT Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| Purified anti-HIV TAT | AC11.AE12 | WB |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-HIV TAT
Western blot analysis of recombinant HIV-TAT protein. Lane ...
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