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- Clone
- QA17A55 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Common γ chain, γc, IL-2 receptor γ subunit
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
-
Human peripheral blood lymphocytes were stained with CD132 (clone QA17A55) purified (filled histogram) or mouse IgG1, κ purified isotype control (open histogram) followed by goat anti-mouse IgG Biotin and Streptavidin-PE
| Cat # | Size | Price | Quantity Check Availability | Save | ||
|---|---|---|---|---|---|---|
| 314602 | 100 µg | £85 | ||||
CD132 is a 64-70 kD type I transmembrane glycoprotein of the Ig superfamily, also known as common γ chain (γc), or IL-2 receptor γ subunit. It is expressed broadly on T- and B-lymphocytes, NK cells, monocytes, and granulocytes. CD132 is an essential component of cytokine receptors for IL-2, IL-4, IL-7, IL-9, IL-15 and IL-21. Ligand binding induces tyrosine phosphorylation and initiates signaling through a JAK/STAT pathway. CD132 mutation results in X-linked severe combined immune deficiency (XSCID).
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Recombinant
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
-
AB_2892384 (BioLegend Cat. No. 314602)
Antigen Details
- Structure
- Type I transmembrane glycoprotein, Ig superfamily 64-70 kD
- Distribution
-
T cells, B cells, NK, monocytes, granulocytes
- Ligand/Receptor
- Component of cytokine receptors for IL-2, IL-4, IL-7, IL-9, IL-15 and IL-21
- Antigen References
-
1. Corrigall V, et al. 2001. J Immunol. 166(6):4141-7.
- Gene ID
- 3561 View all products for this Gene ID
- UniProt
- View information about CD132 on UniProt.org
Related FAQs
Other Formats
View All CD132 Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| PE anti-human CD132 (common γ chain) Recombinant Antibody | QA17A55 | FC |
| Purified anti-human CD132 (common γ chain) Recombinant Antibody | QA17A55 | FC |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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PE anti-human CD132 (common γ chain) Recombinant Antibody
Human peripheral blood lymphocytes were surface stained with... -
Purified anti-human CD132 (common γ chain) Recombinant Antibody
Human peripheral blood lymphocytes were stained with CD132 (...
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