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- Clone
- A20047D (See other available formats)
- Regulatory Status
- RUO
- Other Names
- EPH Receptor A1, Erythropoietin-Producing Hepatoma Receptor, Tyrosine-Protein Kinase Receptor EPH, Ephrin Type-A Receptor 1, EC 2.7.10.1, HEpha1, EPHT1, EPHT, EPH, Erythropoietin-Producing Hepatoma Amplified Sequence
- Isotype
- Rat IgG2a, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
-
Human peripheral blood lymphocytes were stained with anti-human CD4 APC and purified anti-human EphA1 (clone A20047D) (left) or rat IgG2a, κ isotype control (right) followed by PE anti-rat IgG.
| Cat # | Size | Price | Quantity Check Availability | Save | ||
|---|---|---|---|---|---|---|
| 383902 | 100 µg | £288 | ||||
Ephrin type-A receptor 1 (hEpha1), also known as EPH tyrosine kinase belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. The protein consists of 976 a.a. with a molecular weight of 108 kD. The Eph subfamily represents the largest group of receptor protein tyrosine kinases and is divided into two major subclasses: ephrin-A and ephrin-B. They have been implicated in various developmental processes, including axonal guidance, angiogenesis, morphogenesis and carcinogenesis and widely expressed in differentiated epithelial cells in the bone marrow, spleen, thymus, and testis.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
-
AB_2927851 (BioLegend Cat. No. 383902)
Antigen Details
- Structure
- The protein consists of 976 a.a. with a molecular weight of 108 kD.
- Distribution
-
Cytoplasmic and membranous expression in most tissues, including parathyroid gland
- Function
- Kinase, receptor, transferase, tyrosine-protein kinase. EphA1/A2 and ephrin‐A1 are over‐expressed or downregulated in various types of cancer.
- Interaction
- EphA1/A2 and ephrin‐A1 are correlated with tumor malignancy and prognosis.
- Ligand/Receptor
- Ephrin-A1
- Cell Type
- B cells, Endothelial cells, Epithelial cells, T cells, Thymocytes
- Biology Area
- Cancer Biomarkers, Cell Adhesion, Immunology
- Molecular Family
- Protein Kinases/Phosphatase
- Antigen References
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- Katsuaki L and Yoshiro M. 2019. Cancer Sci. 110:841.
- Holen L, et al. 2010. J Leukoc Biol. 87:1059-68.
- Gene ID
- 2041 View all products for this Gene ID
- UniProt
- View information about EphA1 on UniProt.org
Related FAQs
Other Formats
View All EphA1 Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| Purified anti-human EphA1 | A20047D | FC |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-human EphA1
Human peripheral blood lymphocytes were stained with anti-hu...
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