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Purified anti-human HLA-A2 Recombinant Antibody

Pricing & Availability
Clone
QA21A25 (See other available formats)
Regulatory Status
RUO
Other Names
MHC-class I
Isotype
Mouse IgG1, κ
Ave. Rating
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Product Citations
publications
QA21A25_PURE_HLA_A2_Antibody_052623
Human peripheral blood lymphocytes cells were stained with purified anti-human HLA-A2 recombinant (clone QA21A25) (left), or purified mouse IgG1, κ isotype control (right), followed by goat-anti-mouse IgG PE. Cells were costained with anti-human CD3 APC.
  • QA21A25_PURE_HLA_A2_Antibody_052623
    Human peripheral blood lymphocytes cells were stained with purified anti-human HLA-A2 recombinant (clone QA21A25) (left), or purified mouse IgG1, κ isotype control (right), followed by goat-anti-mouse IgG PE. Cells were costained with anti-human CD3 APC.
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386702 100 µg £130
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Description

HLA-A2 is most common in Northern Asia and North America populations. MHC class I antigens associated with β2-microglobulin are expressed by all human nucleated cells. MHC class I molecules are involved in presentation of antigens to CD8+ T cells, playing an important role in cell-mediated immune responses and tumor surveillance.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Human
Antibody Type
Recombinant
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.

RRID
AB_3068052 (BioLegend Cat. No. 386702)

Antigen Details

Structure
Ig superfamily
Distribution

A*02 individuals’ leukocytes

Function
Antigen presentation
Ligand/Receptor
CD8, CD3/TCR
Cell Type
Leukocytes
Biology Area
Immunology
Molecular Family
MHC Antigens
Antigen References
  1. Bjorkman PJ, et al. 2005. J Immunol. 174:6-19.
  2. Pandolfi F, et al. 1991. Cancer Res. 51:3164-70.

 

Gene ID
3105 View all products for this Gene ID
UniProt
View information about HLA-A2 on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 1    Revision Date: 05/26/2023

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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