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- Clone
- QA19A44 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Major Histocompatibility Class II, MHC class II
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
-
Human peripheral blood lymphocytes were stained with CD20 PE and HLA-DR (clone QA19A44) purified (left) or purified mouse IgG1, κ isotype control (right) followed by anti-mouse IgG APC.
| Cat # | Size | Price | Quantity Check Availability | Save | ||
|---|---|---|---|---|---|---|
| 365602 | 100 µg | £89 | ||||
HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kD α (heavy) chain and a 27 kD β (light) chain. It is expressed on B cells, activated T cells, monocytes/macrophages, dendritic cells, and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Recombinant
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
-
AB_2894694 (BioLegend Cat. No. 365602)
Antigen Details
- Structure
- Ig superfamily, MHC class II, heterodimeric transmembrane protein, 36 kD heavy and 27 kD light chain
- Distribution
-
B cells, activated T cells, monocytes/macrophages, dendritic cells, other APCs
- Function
- Peptide presentation
- Ligand/Receptor
- CD3/TCR, CD4
- Cell Type
- Antigen-presenting cells, B cells, Dendritic cells, Macrophages, Monocytes, T cells, Tregs
- Biology Area
- Immunology, Innate Immunity
- Molecular Family
- MHC Antigens
- Antigen References
-
- Levacher M, et al. 1990. Clin Exp Immunol. 81:177.
- Terstappen L, et al. 1990. J Leukocyte Biol. 48:138.
- Edwards JA, et al. 1986. J Immunol. 137:490.
- van Es A, et al. 1984. Transplantation. 37:65.
- O'Doherty U, et al. 1994. Immunology. 82:487.
- Thomas R, et al. 1994. J Immunol. 153:4016.
- Grouard G, et al. 1996. Nature. 384:364.
- Gene ID
- 3122 View all products for this Gene ID 3123 View all products for this Gene ID
- UniProt
- View information about HLA-DR on UniProt.org
Related FAQs
Other Formats
View All HLA-DR Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| Purified anti-human HLA-DR Recombinant Antibody | QA19A44 | FC |
| Brilliant Violet 605™ anti-human HLA-DR Recombinant Antibody | QA19A44 | FC |
| PE anti-human HLA-DR Recombinant Antibody | QA19A44 | FC |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-human HLA-DR Recombinant Antibody
Human peripheral blood lymphocytes were stained with CD20 PE... -
Brilliant Violet 605™ anti-human HLA-DR Recombinant Antibody
Human peripheral blood lymphocytes were stained with anti-hu... -
PE anti-human HLA-DR Recombinant Antibody
Human peripheral blood lymphocytes were stained with anti-hu...
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