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- Clone
- W19338B (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Tyrosine-protein kinase transmembrane receptor ROR2 , Neurotrophic tyrosine kinase, receptor-related 2,
- Isotype
- Rat IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
-
Human erythroleukemic cell line, K562, was stained with purified anti-human ROR2 (clone W19338B) (filled histogram) or rat IgG1, κ isotype control (open histogram) followed by anti-rat IgG PE.
| Cat # | Size | Price | Quantity Check Availability | Save | ||
|---|---|---|---|---|---|---|
| 378502 | 100 µg | £282 | ||||
ROR2 is a receptor protein tyrosine kinase that belongs to the ROR subfamily of cell surface receptors. Both canonical and non-canonical Wnt proteins bind to the ROR2 receptor. ROR2 may play a role during embryonic development in the formation of chondrocytes and cartilage and growth plate development and mediates WNT5A-induced noncanonical Wnts signaling, which induces filopodia formation and cell migration.
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Transfectant AA 1-472
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
ICFC - Verified - Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µL volume. For intracellular immunofluorescent staining with flow cytometric analysis, the suggested use of this reagent is ≤ 0.125 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
-
AB_2910439 (BioLegend Cat. No. 378502)
Antigen Details
- Structure
- Single-pass type I membrane protein
- Distribution
-
Cell membrane
- Function
- ATP binding, coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway, Wnt protein binding, transmembrane receptor protein tyrosine kinase activity
- Interaction
- Frizzled binding, mitogen-activated protein kinase kinase kinase binding
- Ligand/Receptor
- Wnt5a
- Biology Area
- Cell Motility/Cytoskeleton/Structure, Cell Proliferation and Viability
- Molecular Family
- Protein Kinases/Phosphatase
- Antigen References
-
- Masiakowski P, et al. 1992. J Biol Chem. 267:26181-90.
- O'Connell MP, et al. 2010. Oncogene. 29:34-44.
- Liu Y, et al. 2008. J Cell Biochem. 105:497-502.
- Schwarzer W, et al. 2009. Hum Mol Genet. 18:4013-21.
- Gene ID
- 4920 View all products for this Gene ID
- UniProt
- View information about ROR2 on UniProt.org
Related FAQs
Other Formats
View All ROR2 Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| Purified anti-human ROR2 | W19338B | FC,ICFC |
| PE anti-human ROR2 | W19338B | FC |
| APC anti-human ROR2 | W19338B | FC |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-human ROR2
Human erythroleukemic cell line, K562, was stained with puri... -
PE anti-human ROR2
Human erythroleukemic cell line, KS562 was stained with anti... -
APC anti-human ROR2
Human erythroleukemic cell line, K562, was stained with anti...
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