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Purified anti-human TM4SF20 Antibody

Pricing & Availability
Clone
C9 (See other available formats)
Regulatory Status
RUO
Other Names
Transmembrane 4 L Six Family Member 20, SLI5, PRO994, TCCE518
Isotype
Mouse IgG1, κ
Ave. Rating
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Product Citations
publications
C9_Purified_TM4SF20_Antibody_FC_051315
CHO cells transfected with human TM4SF20 were stained with purified anti-human TM4SF20 (clone C9, filled histogram) or purified mouse IgG1, κ isotype control (open histogram), followed by anti-mouse IgG PE.
  • C9_Purified_TM4SF20_Antibody_FC_051315
    CHO cells transfected with human TM4SF20 were stained with purified anti-human TM4SF20 (clone C9, filled histogram) or purified mouse IgG1, κ isotype control (open histogram), followed by anti-mouse IgG PE.
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367202 100 µg £238
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Description

TM4SF20 is a member of the L6 tetraspanin family and is also a protein with four transmembrane along with two extracellular and one intracellular region. Proteins of this family are known to bind integrins, growth hormones, induce insulin secretion, and regulate the development of certain cancers. TM4SF20 is expressed on pancreatic, lung, colon, breast, and ovarian cancers and in the intestinal epithelium and the brain. The deletion of exon 3 of TM4SF20 results in a speech impairment known as Specific Language Impairment-5 (SLI5).

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Human TM4SF20-transfected cells.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

RRID
AB_2565684 (BioLegend Cat. No. 367202)

Antigen Details

Structure
Member of the L6 tetraspanin family, four transmembrane, two extracellular and one intracellular region.
Distribution
Some types of malignant cells, intestinal epithelium, and the brain.
Cell Type
Epithelial cells
Biology Area
Immunology
Antigen References

1. Wiszniewski W, et al. 2013. Am. J. Hum. Genet. 93:197.
2. Lazo P, et al. 2007. Cancer Sci. 98:1666.
3. Kao YR, et al. 2003. Clin. Cancer Res. 9:2807.

Gene ID
79853 View all products for this Gene ID
UniProt
View information about TM4SF20 on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 1    Revision Date: 05/13/2015

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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