- Clone
- C9 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- Transmembrane 4 L Six Family Member 20, SLI5, PRO994, TCCE518
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
Cat # | Size | Price | Quantity Check Availability | Save | ||
---|---|---|---|---|---|---|
367202 | 100 µg | £238 |
TM4SF20 is a member of the L6 tetraspanin family and is also a protein with four transmembrane along with two extracellular and one intracellular region. Proteins of this family are known to bind integrins, growth hormones, induce insulin secretion, and regulate the development of certain cancers. TM4SF20 is expressed on pancreatic, lung, colon, breast, and ovarian cancers and in the intestinal epithelium and the brain. The deletion of exon 3 of TM4SF20 results in a speech impairment known as Specific Language Impairment-5 (SLI5).
Product DetailsProduct Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Human TM4SF20-transfected cells.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
-
AB_2565684 (BioLegend Cat. No. 367202)
Antigen Details
- Structure
- Member of the L6 tetraspanin family, four transmembrane, two extracellular and one intracellular region.
- Distribution
- Some types of malignant cells, intestinal epithelium, and the brain.
- Cell Type
- Epithelial cells
- Biology Area
- Immunology
- Antigen References
-
1. Wiszniewski W, et al. 2013. Am. J. Hum. Genet. 93:197.
2. Lazo P, et al. 2007. Cancer Sci. 98:1666.
3. Kao YR, et al. 2003. Clin. Cancer Res. 9:2807. - Gene ID
- 79853 View all products for this Gene ID
- UniProt
- View information about TM4SF20 on UniProt.org
Related Pages & Pathways
Pages
Other Formats
View All TM4SF20 Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
Purified anti-human TM4SF20 | C9 | FC |
PE anti-human TM4SF20 | C9 | FC |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-human TM4SF20
CHO cells transfected with human TM4SF20 were stained with p... -
PE anti-human TM4SF20
CHO cells transfected with human TM4SF20 were stained with a...
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