- Clone
- SA051D1 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- CXCR6, Chemokine (C-X-C motif) receptor 6, BONZO, STRL33, chemokine receptor 6, CD 186, CXC-R6, CXCR-6, C-X-C chemokine receptor type 6
- Isotype
- Rat IgG2b, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
![SA051D1_PURE_CD186_Antibody_FC_1_112515 SA051D1_PURE_CD186_Antibody_FC_1_112515](https://d1spbj2x7qk4bg.cloudfront.net/Admin/Public/GetImage.ashx?Image=/Files/Images/media_assets/products/product_images/SA051D1_PURE_CD186_Antibody_FC_1_112515.jpg&Width=240&Height=300&altFmImage_path=&Compression=90&Crop=5)
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C57BL/6 mouse splenocytes were stained with CD3 APC and purified CD186 (clone SA051D1, top) or purified rat IgG2b, κ isotype control (bottom), followed by anti-rat IgG PE. -
Cat # | Size | Price | Quantity Check Availability | Save | ||
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151102 | 100 µg | £182 |
CD186, or CXCR6, is a 39 kD G-protein coupled chemokine receptor with seven transmembrane-spanning regions. Its ligand is CXCL16. It is expressed on different T cell subsets and is upregulated in activated T cells. Expression of CXCR6 is correlated with increased inflammatory responses and seems to contribute to liver fibrosis.
Product DetailsProduct Details
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- mCXCR6-transfectants
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
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FC - Quality tested
- Recommended Usage
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Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Product Citations
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- RRID
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AB_2566544 (BioLegend Cat. No. 151102)
Antigen Details
- Structure
- G-protein coupled receptor 1 family.
- Distribution
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T cells and natural killer T (NKT) cells.
- Function
- Chemotaxis and the development of T cells.
- Ligand/Receptor
- CXCL16.
- Cell Type
- NKT cells, T cells
- Biology Area
- Cell Biology, Cell Motility/Cytoskeleton/Structure, Immunology, Neuroinflammation, Neuroscience
- Molecular Family
- CD Molecules, Cytokine/Chemokine Receptors, GPCR
- Antigen References
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1. Kim CH, et al. 2001. J. Clin. Invest. 107:595.
2. Heesch K, et al. 2014. PLoS One. 9:5.
3. Wehr A, et al. 2013. J. Immunol. 190:5226. - Gene ID
- 80901 View all products for this Gene ID
- UniProt
- View information about CD186 on UniProt.org
Other Formats
View All CD186 (CXCR6) Reagents Request Custom ConjugationDescription | Clone | Applications |
---|---|---|
FITC anti-mouse CD186 (CXCR6) | SA051D1 | FC |
Purified anti-mouse CD186 (CXCR6) | SA051D1 | FC |
PE anti-mouse CD186 (CXCR6) | SA051D1 | FC |
APC anti-mouse CD186 (CXCR6) | SA051D1 | FC |
Brilliant Violet 421™ anti-mouse CD186 (CXCR6) | SA051D1 | FC |
Brilliant Violet 711™ anti-mouse CD186 (CXCR6) | SA051D1 | FC |
PE/Dazzle™ 594 anti-mouse CD186 (CXCR6) | SA051D1 | FC |
PE/Cyanine7 anti-mouse CD186 (CXCR6) | SA051D1 | FC |
Biotin anti-mouse CD186 (CXCR6) | SA051D1 | FC |
Alexa Fluor® 647 anti-mouse CD186 (CXCR6) | SA051D1 | FC |
PerCP/Cyanine5.5 anti-mouse CD186 (CXCR6) Antibody | SA051D1 | FC |
APC/Cyanine7 anti-mouse CD186 (CXCR6) Antibody | SA051D1 | FC |
TotalSeq™-A0926 anti-mouse CD186 (CXCR6) | SA051D1 | PG |
TotalSeq™-C0926 anti-mouse CD186 (CXCR6) | SA051D1 | PG |
APC/Fire™ 750 anti-mouse CD186 (CXCR6) | SA051D1 | FC |
TotalSeq™-B0926 anti-mouse CD186 (CXCR6) | SA051D1 | PG |
Spark Red™ 718 anti-mouse CD186 (CXCR6) (Flexi-Fluor™) | SA051D1 | FC |
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Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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FITC anti-mouse CD186 (CXCR6)
C57BL/6 mouse splenocytes were stained with CD3 PE and CD186... -
Purified anti-mouse CD186 (CXCR6)
C57BL/6 mouse splenocytes were stained with CD3 APC and puri... -
PE anti-mouse CD186 (CXCR6)
C57BL/6 mouse splenocytes were stained with CD3 APC and CD18... -
APC anti-mouse CD186 (CXCR6)
C57BL/6 mouse splenocytes were stained with CD3 PE and CD186... -
Brilliant Violet 421™ anti-mouse CD186 (CXCR6)
C57BL/6 mouse splenocytes were stained with CD3 PE and CD186... -
Brilliant Violet 711™ anti-mouse CD186 (CXCR6)
C57BL/6 mouse splenocytes were stained with CD3e APC and CD1... -
PE/Dazzle™ 594 anti-mouse CD186 (CXCR6)
C57BL/6 mouse splenocytes were stained with CD3e APC and CD1... -
PE/Cyanine7 anti-mouse CD186 (CXCR6)
C57BL/6 mouse splenocytes were stained with CD3ε APC... -
Biotin anti-mouse CD186 (CXCR6)
C57BL/6 mouse splenocytes were stained with CD3 APC and CD18... -
Alexa Fluor® 647 anti-mouse CD186 (CXCR6)
C57BL/6 mouse splenocytes were stained with CD3 PE and CD186... -
PerCP/Cyanine5.5 anti-mouse CD186 (CXCR6) Antibody
C57BL/6 mouse splenocytes were stained with CD3ε FITC and an... -
APC/Cyanine7 anti-mouse CD186 (CXCR6) Antibody
C57BL/6 mouse splenocytes were stained with CD3ε FITC and an... -
TotalSeq™-A0926 anti-mouse CD186 (CXCR6)
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TotalSeq™-C0926 anti-mouse CD186 (CXCR6)
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APC/Fire™ 750 anti-mouse CD186 (CXCR6)
C57BL/6 mouse splenocytes were stained with anti-mouse CD3e ... -
TotalSeq™-B0926 anti-mouse CD186 (CXCR6)
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Spark Red™ 718 anti-mouse CD186 (CXCR6) (Flexi-Fluor™)
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