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Purified anti-mouse H-Y TCR Antibody

Pricing & Availability
Clone
MR14-1 (See other available formats)
Regulatory Status
RUO
Other Names
H-Y T cell receptor
Isotype
Mouse IgG1, κ
Ave. Rating
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Product Citations
publications
MR14.1_PE_1_083110
Splenocytes from H-Y TCR transgenic mouse stained with purified MR14-1 conjugated with PE and CD3 APC
  • MR14.1_PE_1_083110
    Splenocytes from H-Y TCR transgenic mouse stained with purified MR14-1 conjugated with PE and CD3 APC
  • MR14.1_PE_2_083110
    C57BL/6 mouse splenocytes stained with MR14.1 PE and CD3 APC
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140602 500 µg £318
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Description

The antibody MR14-1 recognizes an H-Y (male antigen)-specific α/β TCR. The H-Y antigen is expressed by most male cells, and the H-Y TCR transgenic mice have been used to elucidate the mechanisms of T cell selection in the thymus, peripheral tolerance, immunologic memory, and graft rejection.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application References

(PubMed link indicates BioLegend citation)
  1. Wang W, et al. 1995. Science 269:1588. (FC)
  2. Hayashi RJ and Kanagawa O. 1999. Int. Immunol. 11:1581. (FC)
  3. Takase M, et al. 2007. J. Immunol. 179:2163. (FC)
RRID
AB_10644003 (BioLegend Cat. No. 140602)

Antigen Details

Distribution
TCR
Biology Area
Immunology, Adaptive Immunity
Molecular Family
MHC Antigens, TCRs
Antigen References

1. Simpson E, et al. 1997. Annu. Rev. Immunol. 15:39.
2. Dierselhuis M and Goulmy E. 2009. Curr. Opin. Organ. Transplant. 14:419.
3. Roopenian D, et al. 2002. Immunol. Rev. 190:86.

Gene ID
21473 View all products for this Gene ID
UniProt
View information about H-Y TCR on UniProt.org
Go To Top Version: 1    Revision Date: 10/02/2014

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

BioLegend, the BioLegend logo, and all other trademarks are property of BioLegend, Inc. or their respective owners, and all rights are reserved.

 

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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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