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- Clone
- WEN23 (See other available formats)
- Regulatory Status
- RUO
- Other Names
- NCR1, NKP46, LY94
- Isotype
- Mouse IgG1, κ
- Ave. Rating
- Submit a Review
- Product Citations
- publications
-
Rat splenocytes were stained with purified anti-rat CD335 (clone WEN23; left) or purified Mouse IgG1, κ isotype control (right) followed by PE goat anti-mouse IgG. The cells were then stained with APC anti-rat CD161.
| Cat # | Size | Price | Quantity Check Availability | Save | ||
|---|---|---|---|---|---|---|
| 250802 | 100 µg | £101 | ||||
CD335, also known as NKp46, is a glycoprotein of the natural cytotoxicity receptor (NCR) family with 2 Ig-like domains and a short cytoplasmic tail. CD335 expression is restricted to NK cells and a subset of NKT cells; it's not expressed in CD1d-restricted NKT cells. NKp46 functions as a cytotoxicity triggering receptor.
Product DetailsProduct Details
- Verified Reactivity
- Rat
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Rat NKp46 ectodomain recombinant protein
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
-
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
-
AB_2728231 (BioLegend Cat. No. 250802)
Antigen Details
- Structure
- Single-pass type I membrane protein, 46 kD; belongs to the natural cytotoxicity receptor (NCR) family; contains 2 Ig-like (immunoglobulin-like) domains.
- Distribution
-
Mature and immature NK cells, subset of NKT cells, but not on CD1d-restricted NKT cells.
- Function
- NK cells activation
- Ligand/Receptor
- Viral hemagglutinins, heparan sulfate proteoglycans
- Cell Type
- NK cells, NKT cells
- Biology Area
- Immunology, Innate Immunity
- Molecular Family
- CD Molecules
- Antigen References
-
- Westgaard IH, et al. 2004. J. Leuko. Biol. 76:1200.
- Falco M, et al. 1999. Immunol. Lett. 68:411.
- Caligiuri MA. 2008. Blood. 112:461.
- Gene ID
- 117547 View all products for this Gene ID
- UniProt
- View information about CD335 on UniProt.org
Related FAQs
Other Formats
View All CD335 Reagents Request Custom Conjugation| Description | Clone | Applications |
|---|---|---|
| Purified anti-rat CD335 (NKp46) | WEN23 | FC |
| PE anti-rat CD335 (NKp46) | WEN23 | FC |
| FITC anti-rat CD335 (NKp46) | WEN23 | FC |
| APC anti-rat CD335 (NKp46) | WEN23 | FC |
Compare Data Across All Formats
This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.
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Purified anti-rat CD335 (NKp46)
Rat splenocytes were stained with purified anti-rat CD335 (c... -
PE anti-rat CD335 (NKp46)
Rat splenocytes were stained with anti-rat CD335 PE (clone W... -
FITC anti-rat CD335 (NKp46)
Rat splenocytes were stained with anti-rat CD335 FITC (clone... -
APC anti-rat CD335 (NKp46)
Rat splenocytes were stained with rat CD161 FITC and rat CD3...
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