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Purified anti-rat CD68 Recombinant Antibody

Pricing & Availability
Clone
QA20A71 (See other available formats)
Regulatory Status
RUO
Other Names
Macrosialin, GP110, LAMP4, Scavenger Receptor D1 (SR-D1)
Isotype
Mouse IgG1, κ
Ave. Rating
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Product Citations
publications
QA20A71_Purified-_CD68_Antibody_021823
Lew/SS rat peritoneal macrophages were fixed, permeabilized, and intracellularly stained with purified anti-rat CD68 recombinant (clone QA20A71) (left), or purified mouse IgG1, κ isotype control (right), followed by goat anti-mouse IgG PE. Cells were costained with anti-rat CD11b/c APC.
  • QA20A71_Purified-_CD68_Antibody_021823
    Lew/SS rat peritoneal macrophages were fixed, permeabilized, and intracellularly stained with purified anti-rat CD68 recombinant (clone QA20A71) (left), or purified mouse IgG1, κ isotype control (right), followed by goat anti-mouse IgG PE. Cells were costained with anti-rat CD11b/c APC.
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201002 100 µg £197
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Description

Clone QA20A71 recombinant monoclonal antibody recognizes the rat CD68, also known as macrosialin, is a 110 kD integral membrane glycoprotein from the lysosomal-associated membrane protein (LAMP) family. It is predominantly expressed on the intracellular lysomsomes of monocytes and macrophages, and is considered a pan-macrophage marker in the rat. CD68 may have functions relating to phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Rat
Reported Reactivity
Bovine
Antibody Type
Recombinant
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

ICFC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Clone QA20A71 can completely block the binding of parental clone to target cells. Both Cyto-Fast™ Fix/Perm Buffer Set and True-Nuclear™ Transcription Factor Buffer Set work well. This clone does not react to human and mouse.

RRID
AB_2936609 (BioLegend Cat. No. 201002)

Antigen Details

Structure
Lysosome-associated membrane glycoprotein; single-pass type I membrane protein, 110 kD
Distribution

Macrophages, Langerhans cells, and at low levels on dendritic cells

Function
May involved in cell-cell interaction or cell-ligand interaction
Cell Type
Antigen-presenting cells, Dendritic cells, Langerhans cells, Leukocytes, Macrophages
Biology Area
Cell Biology, Immunology, Innate Immunity, Neuroscience, Neuroscience Cell Markers
Molecular Family
Adhesion Molecules, CD Molecules, Innate Immune Signaling
Antigen References
  1. Dijkstra CD, et al. 1985. Immunology. 54:589-99.
  2. Damoiseaux JG, et al. 1994. Immunology. 83:140-7.
Gene ID
287435 View all products for this Gene ID
UniProt
View information about CD68 on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 1    Revision Date: 02/17/2023

For Research Use Only. Not for diagnostic or therapeutic use.

 

This product is supplied subject to the terms and conditions, including the limited license, located at www.biolegend.com/terms) ("Terms") and may be used only as provided in the Terms. Without limiting the foregoing, BioLegend products may not be used for any Commercial Purpose as defined in the Terms, resold in any form, used in manufacturing, or reverse engineered, sequenced, or otherwise studied or used to learn its design or composition without express written approval of BioLegend. Regardless of the information given in this document, user is solely responsible for determining any license requirements necessary for user’s intended use and assumes all risk and liability arising from use of the product. BioLegend is not responsible for patent infringement or any other risks or liabilities whatsoever resulting from the use of its products.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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